Anti-Protein Wnt-5b Antibody (CAB8313)
- SKU:
- CAB8313
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | WNT5B Rabbit Polyclonal Antibody |
抗体コード: | CAB8313 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-359 of human WNT5B (NP_116031.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HepG2, 293T, SH-SY5Y, Mouse liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-359 of human WNT5B (NP_116031.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | VSAA GVVN AISR ACRE GELS TCGC SRTA RPKD LPRD WLWG GCGD NVEY GYRF AKEF VDAR EREK NFAK GSEE QGRV LMNL QNNE AGRR AVYK MADV ACKC HGVS GSCS LKTC WLQL AEFR KVGD RLKE KYDS AAAM RVTR KGRL ELVN SRFT QPTP EDLV YVDP SPDY CLRN ESTG SLGT QGRL CNKT SEGM DGCE LMCC GRGY NQFK SVQV ERCH CKFH WCCF VRCK KCTE IVDQ YICK |
遺伝子ID: | 81029 |
Uniprot: | Q9H1J7 |
セルラーロケーション: | Secreted, extracellular matrix, extracellular space |
計算された分子量: | 40kDa |
観察された分子量: | 50kDa |
同義語: | WNT5B |
バックグラウンド: | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants. |
UniProt Protein Function: | WNT5B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Interacts with PORCN. Belongs to the Wnt family. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 12p13.3 Cellular Component: endoplasmic reticulum lumen; extracellular region; extracellular space; Golgi lumen; plasma membrane Molecular Function:frizzled binding; receptor binding Biological Process: cell fate commitment; chondrocyte differentiation; neuron differentiation; positive regulation of cell migration; Wnt receptor signaling pathway |
NCBI Summary: | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9H1J7 |
NCBI GenInfo Identifier: | 20532427 |
NCBI Gene ID: | 81029 |
NCBI Accession: | Q9H1J7.2 |
UniProt Secondary Accession: | Q9H1J7,Q96S49, Q9BV04, A8K315, D3DUP9, |
UniProt Related Accession: | Q9H1J7 |
Molecular Weight: | 40,323 Da |
NCBI Full Name: | Protein Wnt-5b |
NCBI Synonym Full Names: | Wnt family member 5B |
NCBI Official Symbol: | WNT5B |
NCBI Protein Information: | protein Wnt-5b |
UniProt Protein Name: | Protein Wnt-5b |
UniProt Gene Name: | WNT5B |
UniProt Entry Name: | WNT5B_HUMAN |
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