Anti-PPP3R1 Antibody (CAB0954)
- SKU:
- CAB0954
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-PPP3R1 Antibody |
抗体コード: | CAB0954 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 11-170 of human PPP3R1 (NP_000936.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Mouse brain, Mouse spleen, Mouse lung, Rat brain, SH-SY5Y, SW480, HL-60, MCF7, Rat testis |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 11-170 of human PPP3R1 (NP_000936.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MCSH FDAD EIKR LGKR FKKL DLDN SGSL SVEE FMSL PELQ QNPL VQRV IDIF DTDG NGEV DFKE FIEG VSQF SVKG DKEQ KLRF AFRI YDMD KDGY ISNG ELFQ VLKM MVGN NLKD TQLQ QIVD KTII NADK DGDG RISF EEFC AVVG GLDI HKKM VVDV |
遺伝子ID: | 5534 |
Uniprot: | P63098 |
セルラーロケーション: | Cell membrane, Cytoplasm, Lipid-anchor, Membrane, cytosol, sarcolemma |
計算された分子量: | 19kDa |
観察された分子量: | 15kDa |
同義語: | PPP3R1, CALNB1, CNB, CNB1 |
バックグラウンド: |
UniProt Protein Function: | PPP3R1: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. Belongs to the calcineurin regulatory subunit family. |
UniProt Protein Details: | Protein type:Protein phosphatase, regulatory subunit; Cell development/differentiation; Apoptosis; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2p15 Cellular Component: nucleoplasm; cytosol; calcineurin complex; sarcolemma Molecular Function:calmodulin binding; protein domain specific binding; protein binding; calcium-dependent protein serine/threonine phosphatase activity; calcium ion binding Biological Process: calcineurin-NFAT signaling pathway; positive regulation of NFAT protein import into nucleus; dephosphorylation; apoptosis; innate immune response; positive regulation of transcription from RNA polymerase II promoter |
UniProt Code: | P63098 |
NCBI GenInfo Identifier: | 52000904 |
NCBI Gene ID: | 5534 |
NCBI Accession: | P63098.2 |
UniProt Related Accession: | P63098 |
Molecular Weight: | |
NCBI Full Name: | Calcineurin subunit B type 1 |
NCBI Synonym Full Names: | protein phosphatase 3 regulatory subunit B, alpha |
NCBI Official Symbol: | PPP3R1 |
NCBI Official Synonym Symbols: | CNB; CNB1; CALNB1 |
NCBI Protein Information: | calcineurin subunit B type 1 |
UniProt Protein Name: | Calcineurin subunit B type 1 |
UniProt Synonym Protein Names: | Protein phosphatase 2B regulatory subunit 1; Protein phosphatase 3 regulatory subunit B alpha isoform 1 |
UniProt Gene Name: | PPP3R1 |
UniProt Entry Name: | CANB1_HUMAN |
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