Anti-PPAT Antibody (CAB6698)
- SKU:
- CAB6698
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-PPAT Antibody |
抗体コード: | CAB6698 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PPAT (NP_002694.3). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HepG2, COS-7 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PPAT (NP_002694.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MELE ELGI REEC GVFG CIAS GEWP TQLD VPHV ITLG LVGL QHRG QESA GIVT SDGS SVPT FKSH KGMG LVNH VFTE DNLK KLYV SNLG IGHT RYAT TGKC ELEN CQPF VVET LHGK IAVA HNGE LVNA ARLR KKLL RHGI GLST SSDS EMIT QLLA YTPP QEQD DTPD WVAR IKNL MKEA PTAY SLLI MHRD VIYA VRDP YGNR PLCI GRLI PVSD INDK EKKT SETE GWVV SSES CSFL SIGA RYYR EVLP GEIV EISR HNVQ TLDI ISRS EGNP VAFC |
遺伝子ID: | 5471 |
Uniprot: | Q06203 |
セルラーロケーション: | |
計算された分子量: | 57kDa |
観察された分子量: | 55kDa |
同義語: | PPAT, ATASE, GPAT, PRAT |
バックグラウンド: | The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. |
UniProt Protein Function: | ATASE: Homotetramer. |
UniProt Protein Details: | Protein type:Nucleotide Metabolism - purine; Amino Acid Metabolism - alanine, aspartate and glutamate; Transferase; EC 2.4.2.14 Chromosomal Location of Human Ortholog: 4q12 Cellular Component: cytosol Molecular Function:amidophosphoribosyltransferase activity Biological Process: purine nucleotide biosynthetic process; purine ribonucleoside monophosphate biosynthetic process |
NCBI Summary: | The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. [provided by RefSeq, Mar 2011] |
UniProt Code: | Q06203 |
NCBI GenInfo Identifier: | 548638 |
NCBI Gene ID: | 5471 |
NCBI Accession: | Q06203.1 |
UniProt Related Accession: | Q06203 |
Molecular Weight: | 57,399 Da |
NCBI Full Name: | Amidophosphoribosyltransferase |
NCBI Synonym Full Names: | phosphoribosyl pyrophosphate amidotransferase |
NCBI Official Symbol: | PPAT |
NCBI Official Synonym Symbols: | GPAT; PRAT; ATASE |
NCBI Protein Information: | amidophosphoribosyltransferase |
UniProt Protein Name: | Amidophosphoribosyltransferase |
UniProt Synonym Protein Names: | Glutamine phosphoribosylpyrophosphate amidotransferase; GPAT |
Protein Family: | Pyridoxamine--pyruvate transaminase |
UniProt Gene Name: | PPAT |
UniProt Entry Name: | PUR1_HUMAN |
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