Anti-POU2F3 Antibody (CAB10054)
- SKU:
- CAB10054
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-POU2F3 Antibody |
抗体コード: | CAB10054 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human POU2F3 (NP_055167.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse |
ポジティブサンプル: | Mouse liver, Mouse heart, Mouse stomach |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human POU2F3 (NP_055167.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MVNL ESMH TDIK MSGD VADS TDAR STLS QVEP GNDR NGLD FNRQ IKTE DLSD SLQQ TLSH RPCH LSQG PAMM SGNQ MSGL NASP CQDM ASLH PLQQ LVLV PGHL QSVS QFLL SQTQ PGQQ GLQP NLLP FPQQ QSGL LLPQ TGPG LASQ AFGH PGLP GSSL EPHL EASQ HLPV PKHL PSSG |
遺伝子ID: | 25833 |
Uniprot: | Q9UKI9 |
セルラーロケーション: | Nucleus |
計算された分子量: | 46kDa/47kDa |
観察された分子量: | 47kDa |
同義語: | POU2F3, Epoc-1, OCT-11, OCT11, OTF-11, PLA-1, PLA1, Skn-1a |
バックグラウンド: | This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
UniProt Protein Function: | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Regulated the expression of a number of genes such as SPRR2A or placental lactogen. |
NCBI Summary: | This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] |
UniProt Code: | Q9UKI9 |
NCBI GenInfo Identifier: | 311033416 |
NCBI Gene ID: | 25833 |
NCBI Accession: | Q9UKI9.3 |
UniProt Secondary Accession: | Q9UKI9,Q3MIY3, Q9UKR7, Q9Y504, A8K7H8, B4DY07, F5GWW6 |
UniProt Related Accession: | Q9UKI9 |
Molecular Weight: | 47kDa |
NCBI Full Name: | POU domain, class 2, transcription factor 3 |
NCBI Synonym Full Names: | POU class 2 homeobox 3 |
NCBI Official Symbol: | POU2F3 |
NCBI Official Synonym Symbols: | PLA1; OCT11; PLA-1; Epoc-1; OCT-11; OTF-11; Skn-1a |
NCBI Protein Information: | POU domain, class 2, transcription factor 3 |
UniProt Protein Name: | POU domain, class 2, transcription factor 3 |
UniProt Synonym Protein Names: | Octamer-binding protein 11; Oct-11; Octamer-binding transcription factor 11; OTF-11; Transcription factor PLA-1; Transcription factor Skn-1 |
Protein Family: | POU domain, class 2, transcription factor |
UniProt Gene Name: | POU2F3 |
View AllClose