Anti-POU2AF1 Antibody (CAB6696)
- SKU:
- CAB6696
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-POU2AF1 Antibody |
抗体コード: | CAB6696 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-256 of human POU2AF1 (NP_006226.2). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HT-29, Mouse spleen, Mouse thymus, Rat spleen |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-256 of human POU2AF1 (NP_006226.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MLWQ KPTA PEQA PAPA RPYQ GVRV KEPV KELL RRKR GHAS SGAA PAPT AVVL PHQP LATY TTVG PSCL DMEG SVSA VTEE AALC AGWL SQPT PATL QPLA PWTP YTEY VPHE AVSC PYSA DMYV QPVC PSYT VVGP SSVL TYAS PPLI TNVT TRSS ATPA VGPP LEGP EHQA PLTY FPWP QPLS TLPT STLQ YQPP APAL PGPQ FVQL PISI PEPV LQDM EDPR RAAS SLTI DKLL LEEE DSDA YALN HTLS VEGF |
遺伝子ID: | 5450 |
Uniprot: | Q16633 |
セルラーロケーション: | Nucleus |
計算された分子量: | 27kDa |
観察された分子量: | 27kDa |
同義語: | POU2AF1, BOB1, OBF-1, OBF1, OCAB |
バックグラウンド: |
UniProt Protein Function: | POU2AF1: Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with BCL6. Belongs to the POU2AF1 family. |
UniProt Protein Details: | Protein type:Oncoprotein; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 11q23.1 Cellular Component: nucleus Molecular Function:protein binding; DNA binding; transcription coactivator activity; transcription cofactor activity Biological Process: transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; humoral immune response |
UniProt Code: | Q16633 |
NCBI GenInfo Identifier: | 2833276 |
NCBI Gene ID: | 5450 |
NCBI Accession: | Q16633.1 |
UniProt Secondary Accession: | Q16633,Q14983, B2R8Z9, |
UniProt Related Accession: | Q16633,AAB34937 |
Molecular Weight: | 256 |
NCBI Full Name: | POU domain class 2-associating factor 1 |
NCBI Synonym Full Names: | POU class 2 associating factor 1 |
NCBI Official Symbol: | POU2AF1 |
NCBI Official Synonym Symbols: | BOB1; OBF1; OCAB; OBF-1 |
NCBI Protein Information: | POU domain class 2-associating factor 1; BOB-1; OCA-B; OCT-binding factor 1; B-cell-specific coactivator OBF-1; POU domain, class 2, associating factor 1 |
UniProt Protein Name: | POU domain class 2-associating factor 1 |
UniProt Synonym Protein Names: | B-cell-specific coactivator OBF-1; BOB-1; OCA-B; OCT-binding factor 1 |
Protein Family: | POU domain class 2-associating factor |
UniProt Gene Name: | POU2AF1 |
UniProt Entry Name: | OBF1_HUMAN |
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