Anti-POFUT2 Antibody (CAB12223)
- SKU:
- CAB12223
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-POFUT2 Antibody |
抗体コード: | CAB12223 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-370 of human POFUT2 (NP_056042.1). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-87MG, HepG2, Mouse brain, Mouse heart, Rat brain, Rat heart |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-370 of human POFUT2 (NP_056042.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MVFA RHLR EVGD EFRS RHLN STDD ADRI PFQE DWMK MKVK LGSA LGGP YLGV HLRR KDFI WGHR QDVP SLEG AVRK IRSL MKTH RLDK VFVA TDAV RKEY EELK KLLP EMVR FEPT WEEL ELYK DGGV AII |
遺伝子ID: | 23275 |
Uniprot: | Q9Y2G5 |
セルラーロケーション: | Endoplasmic reticulum, Golgi apparatus |
計算された分子量: | 44kDa/48kDa/49kDa |
観察された分子量: | 50kDa |
同義語: | POFUT2, C21orf80, FUT13 |
バックグラウンド: |
UniProt Protein Function: | POFUT2: Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in thrombospondin type 1 repeats. Belongs to the glycosyltransferase 68 family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 2.4.1.221; Transferase Chromosomal Location of Human Ortholog: 21q22.3 Cellular Component: endoplasmic reticulum membrane; Golgi apparatus Molecular Function:peptide-O-fucosyltransferase activity Biological Process: regulation of secretion |
NCBI Summary: | Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9Y2G5 |
NCBI GenInfo Identifier: | 59803123 |
NCBI Gene ID: | 23275 |
NCBI Accession: | Q9Y2G5.3 |
UniProt Secondary Accession: | Q9Y2G5,Q6PJV1, Q7Z4N0, Q8WWU6, Q9BQS4, Q9BQS5, Q9UFY3 |
UniProt Related Accession: | Q9Y2G5 |
Molecular Weight: | 50kDa |
NCBI Full Name: | GDP-fucose protein O-fucosyltransferase 2 |
NCBI Synonym Full Names: | protein O-fucosyltransferase 2 |
NCBI Official Symbol: | POFUT2 |
NCBI Official Synonym Symbols: | FUT13; C21orf80 |
NCBI Protein Information: | GDP-fucose protein O-fucosyltransferase 2 |
UniProt Protein Name: | GDP-fucose protein O-fucosyltransferase 2 |
UniProt Synonym Protein Names: | Peptide-O-fucosyltransferase 2; O-FucT-2 |
UniProt Gene Name: | POFUT2 |
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