Anti-PLA2G2D Antibody (CAB6690)
- SKU:
- CAB6690
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-PLA2G2D Antibody |
抗体コード: | CAB6690 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-145 of human PLA2G2D (NP_036532.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HL-60, THP-1 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-145 of human PLA2G2D (NP_036532.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | GILN LNKM VKQV TGKM PILS YWPY GCHC GLGG RGQP KDAT DWCC QTHD CCYD HLKT QGCS IYKD YYRY NFSQ GNIH CSDK GSWC EQQL CACD KEVA FCLK RNLD TYQK RLRF YWRP HCRG QTPG C |
遺伝子ID: | 26279 |
Uniprot: | Q9UNK4 |
セルラーロケーション: | Secreted |
計算された分子量: | 16kDa |
観察された分子量: | 20kDa |
同義語: | PLA2G2D, PLA2IID, SPLASH, sPLA2-IID, sPLA2S |
バックグラウンド: | This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms. |
UniProt Protein Function: | PLA2G2D: PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. L-alpha-1-palmitoyl-2- linoleoyl phosphatidylethanolamine is more efficiently hydrolyzed than the other phospholipids examined. Belongs to the phospholipase A2 family. |
UniProt Protein Details: | Protein type:Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - linoleic acid; Lipid Metabolism - ether lipid; Phospholipase; Lipid Metabolism - arachidonic acid; Secreted; Secreted, signal peptide; Lipid Metabolism - glycerophospholipid; EC 3.1.1.4 Chromosomal Location of Human Ortholog: 1p36.12 Cellular Component: extracellular region Molecular Function:phospholipase A2 activity; calcium ion binding Biological Process: phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidic acid biosynthetic process; inflammatory response; lipid catabolic process |
NCBI Summary: | This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012] |
UniProt Code: | Q9UNK4 |
NCBI GenInfo Identifier: | 20139286 |
NCBI Gene ID: | 26279 |
NCBI Accession: | Q9UNK4.2 |
UniProt Secondary Accession: | Q9UNK4,Q9UK01, A8K2Z1, B1AEL9, |
UniProt Related Accession: | Q9UNK4 |
Molecular Weight: | 145 |
NCBI Full Name: | Group IID secretory phospholipase A2 |
NCBI Synonym Full Names: | phospholipase A2, group IID |
NCBI Official Symbol: | PLA2G2D |
NCBI Official Synonym Symbols: | SPLASH; sPLA2S; PLA2IID; sPLA2-IID |
NCBI Protein Information: | group IID secretory phospholipase A2; GIID sPLA2; secretory phospholipase A2s; phosphatidylcholine 2-acylhydrolase 2D; secretory-type PLA, stroma-associated homolog |
UniProt Protein Name: | Group IID secretory phospholipase A2 |
UniProt Synonym Protein Names: | PLA2IID; Phosphatidylcholine 2-acylhydrolase 2D; Secretory-type PLA, stroma-associated homolog |
Protein Family: | Group IID secretory phospholipase |
UniProt Gene Name: | PLA2G2D |
UniProt Entry Name: | PA2GD_HUMAN |
View AllClose