Anti-PLA2G12A Antibody (CAB15902)
- SKU:
- CAB15902
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-PLA2G12A Antibody |
抗体コード: | CAB15902 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PLA2G12A (NP_110448.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | HepG2, HeLa, Mouse pancreas |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PLA2G12A (NP_110448.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MALL SRPA LTLL LLLM AAVV RCQE QAQT TDWR ATLK TIRN GVHK IDTY LNAA LDLL GGED GLCQ YKCS DGSK PFPR YGYK PSPP NGCG SPLF GVHL NIGI |
遺伝子ID: | 81579 |
Uniprot: | Q9BZM1 |
セルラーロケーション: | Cytoplasm, Secreted |
計算された分子量: | 21kDa |
観察された分子量: | 17kDa |
同義語: | PLA2G12A, GXII, PLA2G12, ROSSY |
バックグラウンド: | Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]). |
UniProt Protein Function: | PLA2G12A: PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl- phosphatidylcholine or -phosphatidylethanolamine. Belongs to the phospholipase A2 family. |
UniProt Protein Details: | Protein type:Lipid Metabolism - glycerophospholipid; Secreted; Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - linoleic acid; Secreted, signal peptide; EC 3.1.1.4; Lipid Metabolism - ether lipid; Lipid Metabolism - arachidonic acid; Endoplasmic reticulum; Phospholipase Chromosomal Location of Human Ortholog: 4q25 Cellular Component: extracellular region Molecular Function:phospholipase A2 activity Biological Process: phosphatidic acid biosynthetic process |
NCBI Summary: | Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9BZM1 |
NCBI GenInfo Identifier: | 20143881 |
NCBI Gene ID: | 81579 |
NCBI Accession: | Q9BZM1.1 |
UniProt Secondary Accession: | Q9BZM1,Q9BZ89, |
UniProt Related Accession: | Q9BZM1 |
Molecular Weight: | 21,067 Da |
NCBI Full Name: | Group XIIA secretory phospholipase A2 |
NCBI Synonym Full Names: | phospholipase A2 group XIIA |
NCBI Official Symbol: | PLA2G12A |
NCBI Official Synonym Symbols: | GXII; ROSSY; PLA2G12 |
NCBI Protein Information: | group XIIA secretory phospholipase A2 |
UniProt Protein Name: | Group XIIA secretory phospholipase A2 |
UniProt Synonym Protein Names: | Phosphatidylcholine 2-acylhydrolase 12A |
Protein Family: | Group XIIA secretory phospholipase |
UniProt Gene Name: | PLA2G12A |
UniProt Entry Name: | PG12A_HUMAN |
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