Anti-PKD1L2 Antibody (CAB14954)
- SKU:
- CAB14954
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-PKD1L2 Antibody |
抗体コード: | CAB14954 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-306 of human PKD1L2 (NP_001265352.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse |
ポジティブサンプル: | Mouse lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-306 of human PKD1L2 (NP_001265352.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MGED SPVA MFSW YLDN TPTE QAEP LLDA CRLR GFWP RSLT LLQS NTST LLLN SSFL QSRG EVIR IRAT ALTR HAYG EDTY VIST VPPR EVPA CTIA PEEG TVLT SFAI FCNA STAL GPLE FCFC LESG SCLH CGPE PALP SVYL PLGE ENND FVLT VVIS ATNR AGDT QQTQ AMAK VALG DTCV EDVA FQAA VSEK IPTA LQGE GGPE QLLQ LAKA VSSM LNQE HESQ GSGQ SLSI DVRQ KVRE HVLG SLSA VTTG LEDV QRVQ ELAE VLRE VTCR SKEL TPSA QGSC MGDS WEGA PPAA HVSH AR |
遺伝子ID: | 114780 |
Uniprot: | Q7Z442 |
セルラーロケーション: | Membrane, Multi-pass membrane protein |
計算された分子量: | 26kDa/32kDa/107kDa/197kDa/272kDa |
観察された分子量: | 33kDa |
同義語: | PKD1L2, PC1L2 |
バックグラウンド: | This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. This gene appears to be a polymorphic pseudogene in humans, where some individuals contain a non-functional allele. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | PKD1L2: May function as an ion-channel regulator. May function as a G-protein-coupled receptor. Belongs to the polycystin family. 7 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 16q23.2 Cellular Component: integral to membrane Molecular Function:calcium ion binding; carbohydrate binding Biological Process: ion transport |
NCBI Summary: | This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. This gene appears to be a polymorphic pseudogene in humans, where some individuals contain a non-functional allele. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] |
UniProt Code: | Q7Z442 |
NCBI GenInfo Identifier: | 116006953 |
NCBI Gene ID: | 114780 |
NCBI Accession: | NP_001070248.1 |
UniProt Secondary Accession: | Q7Z442,Q6UEE1, Q6ZN46, Q6ZSP2, Q8N1H9, Q96CL2, Q96Q08 |
UniProt Related Accession: | Q7Z442 |
Molecular Weight: | 26,012 Da |
NCBI Full Name: | polycystic kidney disease protein 1-like 2 isoform c |
NCBI Synonym Full Names: | polycystic kidney disease 1-like 2 (gene/pseudogene) |
NCBI Official Symbol: | PKD1L2 |
NCBI Official Synonym Symbols: | PC1L2 |
NCBI Protein Information: | polycystic kidney disease protein 1-like 2 |
UniProt Protein Name: | Polycystic kidney disease protein 1-like 2 |
UniProt Synonym Protein Names: | PC1-like 2 protein; Polycystin-1L2 |
Protein Family: | Polycystic kidney disease protein |
UniProt Gene Name: | PKD1L2 |
UniProt Entry Name: | PK1L2_HUMAN |
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