Anti-PGAM5 Antibody (CAB16022)
- SKU:
- CAB16022
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
抗体名: | Anti-PGAM5 Antibody |
抗体コード: | CAB16022 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-225 of human PGAM5 (NP_612642.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse brain, Rat liver, Rat testis |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-225 of human PGAM5 (NP_612642.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | KPRA GGDA EPRP AEPP AWAG GARP GPGV WDPN WDRR EPLS LINV RKRN VESG EEEL ASKL DHYK AKAT RHIF LIRH SQYH VDGS LEKD RTLT PLGR EQAE LTGL RLAS LGLK FNKI VHSS MTRA IETT DIIS RHLP GVCK VSTD LLRE GAPI EPDP PVSH WKPE AVQY YEDG ARIE AAFR NYIH RADA RQEE DSYE |
遺伝子ID: | 192111 |
Uniprot: | Q96HS1 |
セルラーロケーション: | |
計算された分子量: | 28kDa/32kDa |
観察された分子量: | 32kDa |
同義語: | PGAM5, BXLBV68 |
バックグラウンド: |
UniProt Protein Function: | PGAM5: Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2- dependent gene expression. Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Hydrolase; EC 3.1.3.16; Mitochondrial Chromosomal Location of Human Ortholog: 12q24.33 Cellular Component: integral to membrane; mitochondrial outer membrane; mitochondrion Molecular Function:GTPase activator activity; phosphoric monoester hydrolase activity; protein complex binding; receptor signaling protein serine/threonine phosphatase activity Biological Process: dephosphorylation; positive regulation of GTPase activity; protein amino acid dephosphorylation |
UniProt Code: | Q96HS1 |
NCBI GenInfo Identifier: | 281604151 |
NCBI Gene ID: | 192111 |
NCBI Accession: | NP_612642.2 |
UniProt Secondary Accession: | Q96HS1,Q96JB0, A9LN06, C9IZY7, |
UniProt Related Accession: | Q96HS1 |
Molecular Weight: | 28,020 Da |
NCBI Full Name: | serine/threonine-protein phosphatase PGAM5, mitochondrial isoform 3 |
NCBI Synonym Full Names: | PGAM family member 5, mitochondrial serine/threonine protein phosphatase |
NCBI Official Symbol: | PGAM5 |
NCBI Official Synonym Symbols: | BXLBV68 |
NCBI Protein Information: | serine/threonine-protein phosphatase PGAM5, mitochondrial |
UniProt Protein Name: | Serine/threonine-protein phosphatase PGAM5, mitochondrial |
UniProt Synonym Protein Names: | Bcl-XL-binding protein v68; Phosphoglycerate mutase family member 5 |
Protein Family: | Serine/threonine-protein phosphatase |
UniProt Gene Name: | PGAM5 |
UniProt Entry Name: | PGAM5_HUMAN |
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