Anti-PGAM1 Antibody (CAB4015)
- SKU:
- CAB4015
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-PGAM1 Antibody |
抗体コード: | CAB4015 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-254 of human PGAM1 (NP_002620.1). |
申し込み: | WB IF |
推奨希釈: | WB 1:1000 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-251MG, LO2, A375, MCF7, NIH/3T3, Mouse brain, Mouse kidney, Mouse liver, Rat spinal cord |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-254 of human PGAM1 (NP_002620.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MAAY KLVL IRHG ESAW NLEN RFSG WYDA DLSP AGHE EAKR GGQA LRDA GYEF DICF TSVQ KRAI RTLW TVLD AIDQ MWLP VVRT WRLN ERHY GGLT GLNK AETA AKHG EAQV KIWR RSYD VPPP PMEP DHPF YSNI SKDR RYAD LTED QLPS CESL KDTI ARAL PFWN EEIV PQIK EGKR VLIA AHGN SLRG IVKH LEGL SEEA IMEL NLPT GIPI VYEL DKNL KPIK PMQF LGDE ETVR KAME AVAA QGKA KK |
遺伝子ID: | 5223 |
Uniprot: | P18669 |
セルラーロケーション: | |
計算された分子量: | 28kDa |
観察された分子量: | 29kDa |
同義語: | PGAM1, HEL-S-35, PGAM-B, PGAMA |
バックグラウンド: | The protein encoded by this gene is a mutase that catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. Two transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | PGAM1: Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. Homodimer. In mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles and type-B in other tissues. Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. |
UniProt Protein Details: | Protein type:EC 5.4.2.4; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Isomerase; EC 3.1.3.13; Phosphatase (non-protein); EC 5.4.2.11 Chromosomal Location of Human Ortholog: 10q25.3 Cellular Component: membrane; cytoplasm; cytosol Molecular Function:protein binding; phosphoglycerate mutase activity; bisphosphoglycerate mutase activity; bisphosphoglycerate phosphatase activity; protein kinase binding Biological Process: respiratory burst; glycolysis; dephosphorylation; regulation of glycolysis; carbohydrate metabolic process; glucose metabolic process; pathogenesis; regulation of pentose-phosphate shunt; gluconeogenesis |
NCBI Summary: | Phosphoglyceric acid mutase (EC 2.7.5.3) is widely distributed in mammalian tissues where it catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway (summary by Chen et al., 1974 [PubMed 4811757]).[supplied by OMIM, Nov 2010] |
UniProt Code: | P18669 |
NCBI GenInfo Identifier: | 130348 |
NCBI Gene ID: | 5223 |
NCBI Accession: | P18669.2 |
UniProt Secondary Accession: | P18669,Q9BWC0, |
UniProt Related Accession: | P18669 |
Molecular Weight: | 254 |
NCBI Full Name: | Phosphoglycerate mutase 1 |
NCBI Synonym Full Names: | phosphoglycerate mutase 1 (brain) |
NCBI Official Symbol: | PGAM1 |
NCBI Official Synonym Symbols: | PGAMA; PGAM-B; HEL-S-35 |
NCBI Protein Information: | phosphoglycerate mutase 1; BPG-dependent PGAM 1; phosphoglycerate mutase isozyme B; epididymis secretory protein Li 35; phosphoglycerate mutase A, nonmuscle form |
UniProt Protein Name: | Phosphoglycerate mutase 1 |
UniProt Synonym Protein Names: | BPG-dependent PGAM 1; Phosphoglycerate mutase isozyme B; PGAM-B |
Protein Family: | Phosphoglycerate mutase |
UniProt Gene Name: | PGAM1 |
UniProt Entry Name: | PGAM1_HUMAN |
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