Anti-PFAS Antibody (CAB17517)
- SKU:
- CAB17517
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
抗体名: | Anti-PFAS Antibody |
抗体コード: | CAB17517 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PFAS (NP_036525.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HeLa, 293T, Jurkat, Raji, U-87MG |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PFAS (NP_036525.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MSPV LHFY VRPS GHEG AAPG HTRR KLQG KLPE LQGV ETEL CYNV NWTA EALP SAEE TKKL MWLF GCPL LLDD VARE SWLL PGSN DLLL EVGP RLNF STPT STNI VSVC RATG LGPV DRVE TTRR YRLS FAHP PSAE VEAI ALAT LHDR MTEQ HFPH PIQS FSPE SMPE PLNG PINI LGEG RLAL EKAN QELG LALD SWDL DFYT KRFQ ELQR NPST VEAF DLAQ SNSE HSRH WFFK GQLH VDGQ KLVH SLFE SIMS TQES SNPN NVLK FCDN SSAI QGKE VRFL RPED PTRP SRFQ QQQG |
遺伝子ID: | 5198 |
Uniprot: | O15067 |
セルラーロケーション: | |
計算された分子量: | |
観察された分子量: | 145kDa |
同義語: | FGAMS, FGAR-AT, FGARAT, GATD8, PURL, PFAS |
バックグラウンド: | Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis. [provided by RefSeq, Jul 2008] |
UniProt Protein Function: | PFAS: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate |
UniProt Protein Details: | Protein type:EC 6.3.5.3; Nucleotide Metabolism - purine; Ligase Chromosomal Location of Human Ortholog: 17p13.1 Cellular Component: cytoplasm; cytosol Molecular Function:ATP binding; phosphoribosylformylglycinamidine synthase activity Biological Process: glutamine metabolic process; purine nucleotide biosynthetic process; purine ribonucleoside monophosphate biosynthetic process; ribonucleoside monophosphate biosynthetic process |
NCBI Summary: | Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis. [provided by RefSeq, Jul 2008] |
UniProt Code: | O15067 |
NCBI GenInfo Identifier: | 317373541 |
NCBI Gene ID: | 5198 |
NCBI Accession: | O15067.4 |
UniProt Secondary Accession: | O15067,A6H8V8, |
UniProt Related Accession: | O15067 |
Molecular Weight: | 144,734 Da |
NCBI Full Name: | Phosphoribosylformylglycinamidine synthase |
NCBI Synonym Full Names: | phosphoribosylformylglycinamidine synthase |
NCBI Official Symbol: | PFAS |
NCBI Official Synonym Symbols: | PURL; FGAMS; FGARAT; FGAR-AT |
NCBI Protein Information: | phosphoribosylformylglycinamidine synthase |
UniProt Protein Name: | Phosphoribosylformylglycinamidine synthase |
UniProt Synonym Protein Names: | Formylglycinamide ribonucleotide amidotransferase; FGAR amidotransferase; FGAR-AT; Formylglycinamide ribotide amidotransferase |
UniProt Gene Name: | PFAS |
UniProt Entry Name: | PUR4_HUMAN |