Anti-PELI1 Antibody (CAB8240)
- SKU:
- CAB8240
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | PELI1 Rabbit Polyclonal Antibody |
抗体コード: | CAB8240 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human PELI1 (NP_065702.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Rat |
ポジティブサンプル: | Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human PELI1 (NP_065702.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MFSP DQEN HPSK APVK YGEL IVLG YNGS LPNG DRGR RKSR FALF KRPK ANGV KPST VHIA CTPQ AAKA ISNK DQHS ISYT LSRA QTVV VEYT HDSN TDMF QIGR STES PIDF VVTD TVPG SQSN SDTQ SVQS TISR FACR IICE RNPP FTAR IYAA GFDS SKNI FLGE KAAK WKTS DGQM DGLT TNGV LVMH PRNG FTED SKPG IWRE ISVC GNVF SLRE TRSA QQRG KMVE IETN QLQD GSLI DLCG AT |
遺伝子ID: | 57162 |
Uniprot: | Q96FA3 |
セルラーロケーション: | |
計算された分子量: | 46kDa |
観察された分子量: | 46kDa |
同義語: | PELI1 |
バックグラウンド: |
UniProt Protein Function: | PELI1: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation. Found in a complex containing TRAF6, IRAK1 and IRAK4. Interacts with MAP3K7. Belongs to the pellino family. |
UniProt Protein Details: | Protein type:Ligase; Ubiquitin ligase; Adaptor/scaffold; EC 6.3.2.-; EC 6.3.2.19; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 2p13.3 Cellular Component: cytosol Molecular Function:protein binding Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade |
UniProt Code: | Q96FA3 |
NCBI GenInfo Identifier: | 37999756 |
NCBI Gene ID: | 57162 |
NCBI Accession: | Q96FA3.2 |
UniProt Secondary Accession: | Q96FA3,Q96SM0, Q9GZY5, Q9HCX0, |
UniProt Related Accession: | Q96FA3 |
Molecular Weight: | 46,286 Da |
NCBI Full Name: | E3 ubiquitin-protein ligase pellino homolog 1 |
NCBI Synonym Full Names: | pellino E3 ubiquitin protein ligase 1 |
NCBI Official Symbol: | PELI1 |
NCBI Protein Information: | E3 ubiquitin-protein ligase pellino homolog 1 |
UniProt Protein Name: | E3 ubiquitin-protein ligase pellino homolog 1 |
UniProt Synonym Protein Names: | Pellino-related intracellular-signaling molecule |
Protein Family: | E3 ubiquitin-protein ligase |
UniProt Gene Name: | PELI1 |
UniProt Entry Name: | PELI1_HUMAN |
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