Anti-PDP2 Antibody (CAB14416)
- SKU:
- CAB14416
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-PDP2 Antibody |
抗体コード: | CAB14416 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 67-250 of human PDP2 (NP_065837.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-87MG, Jurkat, HeLa, Mouse kidney, Mouse liver, Rat liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 67-250 of human PDP2 (NP_065837.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | STEE DDFH LQLS PEQI NEVL RAGE TTHK ILDL ESRV PNSV LRFE SNQL AANS PVED RRGV ASCL QTNG LMFG IFDG HGGH ACAQ AVSE RLFY YVAV SLMS HQTL EHME GAME SMKP LLPI LHWL KHPG DSIY KDVT SVHL DHLR VYWQ ELLD LHME MGLS IEEA LMYS FQRL DSDI SLEI QAPL |
遺伝子ID: | 57546 |
Uniprot: | Q9P2J9 |
セルラーロケーション: | Mitochondrion matrix |
計算された分子量: | 59kDa |
観察された分子量: | 57kDa |
同義語: | PDP2, PDPC 2, PPM2B, PPM2C2 |
バックグラウンド: |
UniProt Protein Function: | PDP2: a protein phosphoserine phosphatase associated with the mitochondrial matrix that activates phosphorylated pyruvate dehydrogenase complex by dephosphorylation. The PDPs play crucial roles in switching metabolic flux from glycolysis towards oxidative phosphorylation. Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. PDP2 consists of only a catalytic subunit. Belongs to the PP2C family. |
UniProt Protein Details: | Protein type:EC 3.1.3.43; Protein phosphatase, Ser/Thr (non-receptor); Mitochondrial Chromosomal Location of Human Ortholog: 16q22.1 Cellular Component: mitochondrial matrix Molecular Function:[pyruvate dehydrogenase (lipoamide)] phosphatase activity; metal ion binding; magnesium-dependent protein serine/threonine phosphatase activity Biological Process: cellular metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate; pyruvate metabolic process |
UniProt Code: | Q9P2J9 |
NCBI GenInfo Identifier: | 41349497 |
NCBI Gene ID: | 57546 |
NCBI Accession: | NP_065837.1 |
UniProt Secondary Accession: | Q9P2J9,A8K924, |
UniProt Related Accession: | Q9P2J9 |
Molecular Weight: | 59,978 Da |
NCBI Full Name: | [Pyruvate dehydrogenase |
NCBI Synonym Full Names: | pyruvate dehyrogenase phosphatase catalytic subunit 2 |
NCBI Official Symbol: | PDP2 |
NCBI Official Synonym Symbols: | PPM2C2 |
NCBI Protein Information: | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial |
UniProt Protein Name: | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial |
UniProt Synonym Protein Names: | Pyruvate dehydrogenase phosphatase catalytic subunit 2; PDPC 2 |
Protein Family: | PWWP domain-containing protein |
UniProt Gene Name: | PDP2 |
UniProt Entry Name: | PDP2_HUMAN |
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