PDP2 Antibody, HRP conjugated (PACO40939)
- SKU:
- PACO40939
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | PDP2 Antibody, HRP conjugated (PACO40939) |
抗体コード: | PACO40939 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial protein (67-529AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Catalyzes the dephosphorylation and concomitant reactivation of the α subunit of the E1 component of the pyruvate dehydrogenase complex. |
シノニム: | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial (PDP 2) (EC 3.1.3.43) (Pyruvate dehydrogenase phosphatase catalytic subunit 2) (PDPC 2), PDP2, KIAA1348 |
UniProt Protein Function: | PDP2: a protein phosphoserine phosphatase associated with the mitochondrial matrix that activates phosphorylated pyruvate dehydrogenase complex by dephosphorylation. The PDPs play crucial roles in switching metabolic flux from glycolysis towards oxidative phosphorylation. Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. PDP2 consists of only a catalytic subunit. Belongs to the PP2C family. |
UniProt Protein Details: | Protein type:EC 3.1.3.43; Protein phosphatase, Ser/Thr (non-receptor); Mitochondrial Chromosomal Location of Human Ortholog: 16q22.1 Cellular Component: mitochondrial matrix Molecular Function:[pyruvate dehydrogenase (lipoamide)] phosphatase activity; metal ion binding; magnesium-dependent protein serine/threonine phosphatase activity Biological Process: cellular metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate; pyruvate metabolic process |
UniProt Code: | Q9P2J9 |
NCBI GenInfo Identifier: | 41349497 |
NCBI Gene ID: | 57546 |
NCBI Accession: | NP_065837.1 |
UniProt Secondary Accession: | Q9P2J9,A8K924, |
UniProt Related Accession: | Q9P2J9 |
Molecular Weight: | 59,978 Da |
NCBI Full Name: | [Pyruvate dehydrogenase |
NCBI Synonym Full Names: | pyruvate dehyrogenase phosphatase catalytic subunit 2 |
NCBI Official Symbol: | PDP2 |
NCBI Official Synonym Symbols: | PPM2C2 |
NCBI Protein Information: | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial |
UniProt Protein Name: | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial |
UniProt Synonym Protein Names: | Pyruvate dehydrogenase phosphatase catalytic subunit 2; PDPC 2 |
Protein Family: | PWWP domain-containing protein |
UniProt Gene Name: | PDP2 |
UniProt Entry Name: | PDP2_HUMAN |