Anti-PARD6B Antibody (CAB5060)

(No reviews yet) Write a Review
SKU:
CAB5060
Product type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
PARD6B
Synonyms:
PAR6B
€0.00
Frequently bought together:

Description

抗体名:PARD6B Rabbit pAb
抗体コード:CAB5060
サイズ:20uL, 50uL, 100uL
同義語:PARD6B, PAR6B
申し込み:WB
反応性:Human
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 253-372 of human PARD6B (NP_115910.1).
申し込み:WB
推奨される希釈:WB 1:1000 - 1:4000
反応性:Human
ポジティブサンプル:SH-SY5Y, MCF7, HepG2
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 253-372 of human PARD6B (NP_115910.1).
精製方法:Affinity purification
保管所:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:NNVV RNSR TSGS SGQS TDNS LLGY PQQI EPSF EPED EDSE EDDI IIED NGVP QQIP KAVP NTES LESL TQIE LSFE SGQN GFIP SNEV SLAA IASS SNTE FETH APDQ KLLE EDGT IITL
遺伝子ID:84612
Uniprot:Q9BYG5
セルラーロケーション:Cell junction, Cell membrane, Cytoplasm, tight junction
計算された分子量:12kDa/41kDa
観察された分子量:41kDa
UniProt Protein Function:PARD6B: Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Belongs to the PAR6 family.
UniProt Protein Details:

Protein type:Cell adhesion

Chromosomal Location of Human Ortholog: 20q13.13

Cellular Component: protein complex; tight junction; apical part of cell; cytoplasm; plasma membrane; cell cortex; nucleus; cytosol

Molecular Function:protein binding

Biological Process: intercellular junction assembly; intercellular junction assembly and maintenance; axonogenesis; cell division; establishment and/or maintenance of cell polarity; protein complex assembly; cell cycle; regulation of cell migration

NCBI Summary:This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. [provided by RefSeq, Jul 2008]
UniProt Code:Q9BYG5
NCBI GenInfo Identifier:30913176
NCBI Gene ID:84612
NCBI Accession:Q9BYG5.1
UniProt Secondary Accession:Q9BYG5,Q9Y510, A2A2A7,
UniProt Related Accession:Q9BYG5
Molecular Weight:372
NCBI Full Name:Partitioning defective 6 homolog beta
NCBI Synonym Full Names:par-6 family cell polarity regulator beta
NCBI Official Symbol:PARD6B  
NCBI Official Synonym Symbols:PAR6B  
NCBI Protein Information:partitioning defective 6 homolog beta; PAR-6 beta; par-6 partitioning defective 6 homolog beta
UniProt Protein Name:Partitioning defective 6 homolog beta
Protein Family:Partitioning defective
UniProt Gene Name:PARD6B  
UniProt Entry Name:PAR6B_HUMAN
View AllClose

View AllClose

Related Products