Anti-OGDHL Antibody (CAB15475)
- SKU:
- CAB15475
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-OGDHL Antibody |
抗体コード: | CAB15475 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human OGDHL (NP_060715.2). |
申し込み: | WB IHC |
推奨希釈: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | LO2, Mouse kidney, Mouse brain, Rat kidney |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human OGDHL (NP_060715.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MSQL RLLP SRLG VQAA RLLA AHDV PVFG WRSR SSGP PATF PSSK GGGG SSYM EEMY FAWL ENPQ SVHK SWDS FFRE ASEE AFSG SAQP RPPS VVHE SRSA VSSR TKTS KL |
遺伝子ID: | 55753 |
Uniprot: | Q9ULD0 |
セルラーロケーション: | Mitochondrion matrix |
計算された分子量: | 91kDa/108kDa/114kDa |
観察された分子量: | 120kDa |
同義語: | OGDHL |
バックグラウンド: | The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glucose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria. The encoded protein down-regulates the AKT signaling cascade and can suppress the growth of cervical cancer cells. |
UniProt Protein Function: | OGDHL: Belongs to the alpha-ketoglutarate dehydrogenase family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Mitochondrial; Oxidoreductase; EC 1.2.4.-; Amino Acid Metabolism - lysine degradation; Amino Acid Metabolism - tryptophan; Carbohydrate Metabolism - citrate (TCA) cycle Chromosomal Location of Human Ortholog: 10q11.23 Cellular Component: mitochondrion; mitochondrial matrix; oxoglutarate dehydrogenase complex; cytosol Molecular Function:protein binding; metal ion binding; thiamin pyrophosphate binding; oxoglutarate dehydrogenase (succinyl-transferring) activity Biological Process: glycolysis; tricarboxylic acid cycle |
NCBI Summary: | The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glucose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria. The encoded protein down-regulates the AKT signaling cascade and can suppress the growth of cervical cancer cells. [provided by RefSeq, Dec 2016] |
UniProt Code: | Q9ULD0 |
NCBI GenInfo Identifier: | 160419019 |
NCBI Gene ID: | 55753 |
NCBI Accession: | Q9ULD0.3 |
UniProt Related Accession: | Q9ULD0 |
Molecular Weight: | 91kDa; 108kDa; 114kDa |
NCBI Full Name: | 2-oxoglutarate dehydrogenase-like, mitochondrial |
NCBI Synonym Full Names: | oxoglutarate dehydrogenase like |
NCBI Official Symbol: | OGDHL |
NCBI Protein Information: | 2-oxoglutarate dehydrogenase-like, mitochondrial |
UniProt Protein Name: | 2-oxoglutarate dehydrogenase-like, mitochondrial |
UniProt Synonym Protein Names: | 2-oxoglutarate dehydrogenase complex component E1-like; OGDC-E1-like; Alpha-ketoglutarate dehydrogenase-like |
Protein Family: | 2-oxoglutarate dehydrogenase |
UniProt Gene Name: | OGDHL |
UniProt Entry Name: | OGDHL_HUMAN |
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