Anti-NR4A2 Antibody (CAB17318)
- SKU:
- CAB17318
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-NR4A2 Antibody |
抗体コード: | CAB17318 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | A synthetic Peptide of human NR4A2. |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: |
免疫原: | A synthetic Peptide of human NR4A2. |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 4929 |
Uniprot: | P43354 |
セルラーロケーション: | Cytoplasm, Nucleus |
計算された分子量: | 59kDa/66kDa |
観察された分子量: | Refer to figures |
同義語: | NR4A2, HZF-3, NOT, NURR1, RNR1, TINUR |
バックグラウンド: | This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. |
UniProt Protein Function: | Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. |
NCBI Summary: | This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
UniProt Code: | P43354 |
NCBI GenInfo Identifier: | 187423888 |
NCBI Gene ID: | 4929 |
NCBI Accession: | NP_006177.1 |
UniProt Secondary Accession: | P43354,Q16311, Q53RZ2, Q6NXU0, |
UniProt Related Accession: | P43354 |
Molecular Weight: | 59,809 Da |
NCBI Full Name: | Homo sapiens nuclear receptor subfamily 4, group A, member 2 (NR4A2), mRNA |
NCBI Synonym Full Names: | nuclear receptor subfamily 4, group A, member 2 |
NCBI Official Symbol: | NR4A2 |
NCBI Official Synonym Symbols: | NOT; RNR1; HZF-3; NURR1; TINUR |
NCBI Protein Information: | nuclear receptor subfamily 4 group A member 2; NGFI-B/nur77 beta-type transcription factor homolog; T-cell nuclear receptor NOT; immediate-early response protein NOT; intermediate-early receptor protein; nuclear receptor related 1; nur related protein-1 |
UniProt Protein Name: | Nuclear receptor subfamily 4 group A member 2 |
UniProt Synonym Protein Names: | Immediate-early response protein NOT; Orphan nuclear receptor NURR1; Transcriptionally-inducible nuclear receptor |
Protein Family: | Nuclear receptor subfamily |
UniProt Gene Name: | NR4A2 |
UniProt Entry Name: | NR4A2_HUMAN |
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