Anti-NOSTRIN Antibody (CAB15938)
- SKU:
- CAB15938
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-NOSTRIN Antibody |
抗体コード: | CAB15938 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 207-506 of human NOSTRIN (NP_001034813.2). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse |
ポジティブサンプル: | Mouse brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 207-506 of human NOSTRIN (NP_001034813.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | NCYQ SILE LEKE RIQL LCNN LNQY SQHI SLFG QTLT TCHT QIHC AISK IDIE KDIQ AVME ETAI LSTE NKSE FLLT DYFE EDPN SAMD KERR KSLL KPKL LRLQ RDIE KASK DKEG LERM LKTY SSTS SFSD AKSQ KDTA ALMD ENNL KLDL LEAN SYKL SSML AELE QRPQ PSHP CSNS IFRW REKE HTHS YVKI SRPF LMKR LENI VSKA SSGG QSNP GSST PAPG AAQL SSRL CKAL YSFQ ARQD DELN LEKG DIVI IHEK KEGG WWFG SLNG KKGH FPAA YVEE LPSN AGNT ATKA |
遺伝子ID: | 115677 |
Uniprot: | Q8IVI9 |
セルラーロケーション: | Cell membrane, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Nucleus, Peripheral membrane protein, cytoskeleton |
計算された分子量: | 48kDa/54kDa/57kDa/64kDa |
観察された分子量: | 57kDa |
同義語: | NOSTRIN, DaIP2, nostrin |
バックグラウンド: | Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production. |
UniProt Protein Function: | NOSTRIN: Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 2q31.1 Cellular Component: plasma membrane Molecular Function:protein binding Biological Process: regulation of nitric-oxide synthase activity |
NCBI Summary: | Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM, Apr 2004] |
UniProt Code: | Q8IVI9 |
NCBI GenInfo Identifier: | 317373401 |
NCBI Gene ID: | 115677 |
NCBI Accession: | Q8IVI9.2 |
UniProt Secondary Accession: | Q8IVI9,Q27HG3, Q53S62, Q96CJ9, A8K2I9, B3KSF5, E7EPT9 |
UniProt Related Accession: | Q8IVI9 |
Molecular Weight: | 64,364 Da |
NCBI Full Name: | Nostrin |
NCBI Synonym Full Names: | nitric oxide synthase trafficking |
NCBI Official Symbol: | NOSTRIN |
NCBI Official Synonym Symbols: | DaIP2 |
NCBI Protein Information: | nostrin |
UniProt Protein Name: | Nostrin |
UniProt Synonym Protein Names: | BM247 homolog; Nitric oxide synthase traffic inducer; Nitric oxide synthase trafficker; eNOS-trafficking inducer |
Protein Family: | Nostrin |
UniProt Gene Name: | NOSTRIN |
UniProt Entry Name: | NOSTN_HUMAN |
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