Anti-NKIRAS1 Antibody (CAB14878)
- SKU:
- CAB14878
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-NKIRAS1 Antibody |
抗体コード: | CAB14878 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 118-192 of human NKIRAS1 (NP_065078.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse brain, Mouse testis, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 118-192 of human NKIRAS1 (NP_065078.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LGNK IDLS EQRQ VDAE VAQQ WAKS EKVR LWEV TVTD RKTL IEPF TLLA SKLS QPQS KSSF PLPG RKNK GNSN SEN |
遺伝子ID: | 28512 |
Uniprot: | Q9NYS0 |
セルラーロケーション: | Cytoplasm |
計算された分子量: | 21kDa |
観察された分子量: | 22kDa |
同義語: | NKIRAS1, KBRAS1, kappaB-Ras1 |
バックグラウンド: |
UniProt Protein Function: | NKIRAS1: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily. |
UniProt Protein Details: | Protein type:G protein, monomeric, Ras; G protein; G protein, monomeric Chromosomal Location of Human Ortholog: 3p24.2 |
UniProt Code: | Q9NYS0 |
NCBI GenInfo Identifier: | 74753075 |
NCBI Gene ID: | 28512 |
NCBI Accession: | Q9NYS0.1 |
UniProt Secondary Accession: | Q9NYS0,Q96K18, |
UniProt Related Accession: | Q9NYS0 |
Molecular Weight: | 21,643 Da |
NCBI Full Name: | NF-kappa-B inhibitor-interacting Ras-like protein 1 |
NCBI Synonym Full Names: | NFKB inhibitor interacting Ras like 1 |
NCBI Official Symbol: | NKIRAS1 |
NCBI Official Synonym Symbols: | KBRAS1; kappaB-Ras1 |
NCBI Protein Information: | NF-kappa-B inhibitor-interacting Ras-like protein 1 |
UniProt Protein Name: | NF-kappa-B inhibitor-interacting Ras-like protein 1 |
UniProt Synonym Protein Names: | I-kappa-B-interacting Ras-like protein 1; Kappa B-Ras protein 1; KappaB-Ras1 |
Protein Family: | NF-kappa-B inhibitor-interacting Ras-like protein |
UniProt Gene Name: | NKIRAS1 |
UniProt Entry Name: | KBRS1_HUMAN |
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