Anti-NELL1 Antibody (CAB10358)
- SKU:
- CAB10358
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
抗体名: | Anti-NELL1 Antibody |
抗体コード: | CAB10358 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-420 of human NELL1 (NP_006148.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-87MG, 293T, Mouse pancreas, Rat brain, Rat small intestine |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-420 of human NELL1 (NP_006148.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | HLLL HVDC NRIY ERVI DPPD TNLP PGIN LWLG QRNQ KHGL FKGI IQDG KIIF MPNG YITQ CPNL NHTC PTCS DFLS LVQG IMDL QELL AKMT AKLN YAET RLSQ LENC HCEK TCQV SGLL YRDQ DSWV DGDH CRNC TCKS GAVE CRRM SCPP LNCS PDSL PVHI AGQC CKVC RPKC IYGG KVLA EGQR ILTK SCRE CRGG VLVK ITEM CPPL NCSE KDHI LPEN QCCR VCRG HNFC AEGP KCGE NSEC KNWN TKAT CECK S |
遺伝子ID: | 4745 |
Uniprot: | Q92832 |
セルラーロケーション: | Cytoplasm, Nucleus envelope, Secreted |
計算された分子量: | 84kDa/89kDa |
観察された分子量: | 80kDa |
同義語: | NELL1, IDH3GL, NRP1 |
バックグラウンド: | This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | NELL1: Plays a role in the control of cell growth and differentiation. Promotes osteoblast cell differentiation and terminal mineralization. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 11p15.1 Cellular Component: cytoplasm; nuclear envelope; perinuclear region of cytoplasm Molecular Function:protein binding Biological Process: negative regulation of osteoblast proliferation; nervous system development; positive regulation of bone mineralization; positive regulation of osteoblast differentiation; regulation of gene expression |
NCBI Summary: | This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] |
UniProt Code: | Q92832 |
NCBI GenInfo Identifier: | 311033486 |
NCBI Gene ID: | 4745 |
NCBI Accession: | Q92832.4 |
UniProt Secondary Accession: | Q92832,Q4VB90, Q4VB91, Q6NSY8, Q9Y472, B2CKC1, |
UniProt Related Accession: | Q92832 |
Molecular Weight: | 84,377 Da |
NCBI Full Name: | Protein kinase C-binding protein NELL1 |
NCBI Synonym Full Names: | neural EGFL like 1 |
NCBI Official Symbol: | NELL1 |
NCBI Official Synonym Symbols: | NRP1; IDH3GL |
NCBI Protein Information: | protein kinase C-binding protein NELL1 |
UniProt Protein Name: | Protein kinase C-binding protein NELL1 |
UniProt Synonym Protein Names: | NEL-like protein 1; Nel-related protein 1 |
Protein Family: | Protein kinase C-binding protein |
UniProt Gene Name: | NELL1 |
UniProt Entry Name: | NELL1_HUMAN |
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