Anti-MTRR Antibody (CAB1462)
- SKU:
- CAB1462
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-MTRR Antibody |
抗体コード: | CAB1462 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-230 of human MTRR (NP_002445.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | A-549, HeLa, LO2, 293T |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-230 of human MTRR (NP_002445.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | TAPL VVVV STTG TGDP PDTA RKFV KEIQ NQTL PVDF FAHL RYGL LGLG DSEY TYFC NGGK IIDK RLQE LGAR HFYD TGHA DDCV GLEL VVEP WIAG LWPA LRKH FRSS RGQE EISG ALPV ASPA SSRT DLVK SELL HIES QVEL LRFD DSGR KDSE VLKQ NAVN SNQS NVVI EDFE SSLT R |
遺伝子ID: | 4552 |
Uniprot: | Q9UBK8 |
セルラーロケーション: | Cytoplasm, Cytoplasm |
計算された分子量: | 6kDa/77kDa/80kDa |
観察された分子量: | 80kDa |
同義語: | MTRR, MSR, cblE |
バックグラウンド: | This gene encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants. |
NCBI Summary: | This gene encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015] |
UniProt Code: | Q9UBK8 |
NCBI GenInfo Identifier: | 169790958 |
NCBI Gene ID: | 4552 |
NCBI Accession: | NP_002445 |
UniProt Related Accession: | Q9UBK8 |
Molecular Weight: | |
NCBI Full Name: | methionine synthase reductase |
NCBI Synonym Full Names: | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase |
NCBI Official Symbol: | MTRR |
NCBI Official Synonym Symbols: | MSR; cblE |
NCBI Protein Information: | methionine synthase reductase |
UniProt Protein Name: | Methionine synthase reductase |
Protein Family: | Mycothione reductase |
UniProt Gene Name: | MTRR |
UniProt Entry Name: | MTRR_HUMAN |
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