Anti-MRPS27 Antibody (CAB11667)
- SKU:
- CAB11667
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-MRPS27 Antibody |
抗体コード: | CAB11667 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 255-414 of human MRPS27 (NP_055899.2). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | A-549, LO2, U-87MG, HeLa, A-431, HT-29, Mouse liver, Rat heart |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 255-414 of human MRPS27 (NP_055899.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | YLDR ALQV MEKV AASP EDIK LCRE ALDV LGAV LKAL TSAD GASE EQSQ NDED NQGS EKLV EQLD IEET EQSK LPQY LERF KALH SKLQ ALGK IESE GLLS LTTQ LVKE KLST CEAE DIAT YEQN LQQW HLDL VQLI QREQ QQRE QAKQ EYQA QKAA KASA |
遺伝子ID: | 23107 |
Uniprot: | Q92552 |
セルラーロケーション: | Mitochondrion |
計算された分子量: | 47kDa/49kDa |
観察された分子量: | 48kDa |
同義語: | MRPS27, MRP-S27, S27mt |
バックグラウンド: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that may be a functional partner of the death associated protein 3 (DAP3). Alternative splicing results in multiple transcript variants encoding different isoforms. |
UniProt Protein Function: | MRPS27: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins. |
UniProt Protein Details: | Protein type:Ribosomal; Mitochondrial; Translation Chromosomal Location of Human Ortholog: 5q13.2 Cellular Component: mitochondrial inner membrane; ribosome Molecular Function:protein binding Biological Process: mitochondrial translation; organelle organization and biogenesis |
NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that may be a functional partner of the death associated protein 3 (DAP3). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2013] |
UniProt Code: | Q92552 |
NCBI GenInfo Identifier: | 209572725 |
NCBI Gene ID: | 23107 |
NCBI Accession: | Q92552.3 |
UniProt Secondary Accession: | Q92552,Q6P1S1, B4DRT2, |
UniProt Related Accession: | Q92552 |
Molecular Weight: | 414 |
NCBI Full Name: | 28S ribosomal protein S27, mitochondrial |
NCBI Synonym Full Names: | mitochondrial ribosomal protein S27 |
NCBI Official Symbol: | MRPS27 |
NCBI Official Synonym Symbols: | S27mt; MRP-S27 |
NCBI Protein Information: | 28S ribosomal protein S27, mitochondrial; mitochondrial 28S ribosomal protein S27 |
UniProt Protein Name: | 28S ribosomal protein S27, mitochondrial |
Protein Family: | 28S ribosomal protein |
UniProt Gene Name: | MRPS27 |
UniProt Entry Name: | RT27_HUMAN |
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