Anti-MPZL1 Antibody (CAB13059)
- SKU:
- CAB13059
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-MPZL1 Antibody |
抗体コード: | CAB13059 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-269 of human MPZL1 (NP_003944.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | BxPC-3, HeLa, Mouse brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-269 of human MPZL1 (NP_003944.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MAAS AGAG AVIA APDS RRWL WSVL AAAL GLLT AGVS ALEV YTPK EIFV ANGT QGKL TCKF KSTS TTGG LTSV SWSF QPEG ADTT VSFF HYSQ GQVY LGNY PPFK DRIS WAGD LDKK DASI NIEN MQFI HNGT YICD VKNP PDIV VQPG HIRL YVVE KENL PVFP VWVV VGIV TAVV LGLT LLIS MILA VLYR RKNS KRDY TGCS TSES LSPV KQAP RKSP SDTE GLVK SLPS GSHQ GPVI YAQL DHSG GHHS DKIN KSES VVYA DIRK N |
遺伝子ID: | 9019 |
Uniprot: | O95297 |
セルラーロケーション: | Membrane, Single-pass type I membrane protein |
計算された分子量: | 12kDa/15kDa/22kDa/28kDa/29kDa |
観察された分子量: | 16kDa |
同義語: | MPZL1, MPZL1b, PZR, PZR1b, PZRa, PZRb |
バックグラウンド: |
UniProt Protein Function: | PZR: an immunoglobulin superfamily cell surface protein. Contains two tyrosine-based inhibition motifs (ITIMs) responsible for binding of SHP-2. When phosphorylated, it can specifically bind SHP-2, blocking its translocation, and interupting its function. Treatment of several cell lines with ConA caused tyrosine phosphorylation of PZR. Two alternatively spliced isoforms have been reported. One isoform, PZR1b, lacks the ITIMs and has a dominant negative effect upon full-length PZR and its recruitment of SHP-2. |
UniProt Protein Details: | Protein type:Adaptor/scaffold; Membrane protein, integral Chromosomal Location of Human Ortholog: 1q24.2 Cellular Component: focal adhesion; cell surface; integral to plasma membrane Molecular Function:protein binding; structural molecule activity Biological Process: cell-cell signaling; transmembrane receptor protein tyrosine kinase signaling pathway |
UniProt Code: | O95297 |
NCBI GenInfo Identifier: | 226054871 |
NCBI Gene ID: | 9019 |
NCBI Accession: | NP_001139663.1 |
UniProt Related Accession: | O95297 |
Molecular Weight: | Observed: 29 kDaPredicted: 30 kDa |
NCBI Full Name: | myelin protein zero-like protein 1 isoform c |
NCBI Synonym Full Names: | myelin protein zero like 1 |
NCBI Official Symbol: | MPZL1 |
NCBI Official Synonym Symbols: | PZR; PZRa; PZRb; PZR1b; MPZL1b |
NCBI Protein Information: | myelin protein zero-like protein 1 |
UniProt Protein Name: | Myelin protein zero-like protein 1 |
UniProt Synonym Protein Names: | Protein zero-related |
UniProt Gene Name: | MPZL1 |
UniProt Entry Name: | MPZL1_HUMAN |
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