Anti-MID2 Antibody (CAB8325)
- SKU:
- CAB8325
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-MID2 Antibody |
抗体コード: | CAB8325 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 476-705 of human MID2 (NP_438112.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | BT-474, 293T, U-251MG, Mouse lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 476-705 of human MID2 (NP_438112.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | GTRY IFIV KAIN QAGS RNSE PTRL KTNS QPFK LDPK MTHK KLKI SNDG LQME KDES SLKK SHTP ERFS GTGC YGAA GNIF IDSG CHYW EVVM GSST WYAI GIAY KSAP KNEW IGKN ASSW VFSR CNSN FVVR HNNK EMLV DVPP HLKR LGVL LDYD NNML SFYD PANS LHLH TFDV TFIL PVCP TFTI WNKS LMIL SGLP APDF IDYP ERQE CNCR PQES PYVS GMKT CH |
遺伝子ID: | 11043 |
Uniprot: | Q9UJV3 |
セルラーロケーション: | Cytoplasm, cytoskeleton |
計算された分子量: | 79kDa/83kDa |
観察された分子量: | 83kDa |
同義語: | MID2, FXY2, MRX101, RNF60, TRIM1, midline 2 |
バックグラウンド: | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gene results in two transcript variants encoding different isoforms. |
UniProt Protein Function: | MID2: is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009] |
UniProt Protein Details: | Protein type:Microtubule-binding; EC 6.3.2.-; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: Xq22.3 Cellular Component: microtubule Molecular Function:microtubule binding; phosphoprotein binding; protein heterodimerization activity; protein homodimerization activity Biological Process: activation of NF-kappaB transcription factor; innate immune response; negative regulation of viral transcription; negative regulation of virion penetration into host cell; positive regulation of autophagy; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription factor activity Disease: Mental Retardation, X-linked 101 |
NCBI Summary: | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009] |
UniProt Code: | Q9UJV3 |
NCBI GenInfo Identifier: | 294862489 |
NCBI Gene ID: | 11043 |
NCBI Accession: | Q9UJV3.3 |
UniProt Secondary Accession: | Q9UJV3,Q5JYF5, Q8WWK1, Q9UJR9, A6NEL8, A6PVI5, |
UniProt Related Accession: | Q9UJV3 |
Molecular Weight: | 79,865 Da |
NCBI Full Name: | Probable E3 ubiquitin-protein ligase MID2 |
NCBI Synonym Full Names: | midline 2 |
NCBI Official Symbol: | MID2 |
NCBI Official Synonym Symbols: | FXY2; RNF60; TRIM1; MRX101 |
NCBI Protein Information: | probable E3 ubiquitin-protein ligase MID2 |
UniProt Protein Name: | Probable E3 ubiquitin-protein ligase MID2 |
UniProt Synonym Protein Names: | Midin-2; Midline defect 2; Midline-2; RING finger protein 60; Tripartite motif-containing protein 1 |
Protein Family: | Cell wall integrity sensor |
UniProt Gene Name: | MID2 |
UniProt Entry Name: | TRIM1_HUMAN |
View AllClose