Anti-MGAT1 Antibody (CAB6387)
- SKU:
- CAB6387
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-MGAT1 Antibody |
抗体コード: | CAB6387 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 156-445 of human MGAT1 (NP_001108092.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Mouse liver, Mouse kidney, Mouse heart, Rat liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 156-445 of human MGAT1 (NP_001108092.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | GSAV THIR QPDL SSIA VPPD HRKF QGYY KIAR HYRW ALGQ VFRQ FRFP AAVV VEDD LEVA PDFF EYFR ATYP LLKA DPSL WCVS AWND NGKE QMVD ASRP ELLY RTDF FPGL GWLL LAEL WAEL EPKW PKAF WDDW MRRP EQRQ GRAC IRPE ISRT MTFG RKGV SHGQ FFDQ HLKF IKLN QQFV HFTQ LDLS YLQR EAYD RDFL ARVY GAPQ LQVE KVRT NDRK ELGE VRVQ YTGR DSFK AFAK ALGV MDDL KSGV PRAG YRGI VTFQ FRGR RVHL APPL TWEG YDPS WN |
遺伝子ID: | 4245 |
Uniprot: | P26572 |
セルラーロケーション: | Golgi apparatus membrane, Single-pass type II membrane protein |
計算された分子量: | 50kDa |
観察された分子量: | 60kDa |
同義語: | MGAT1, GLCNAC-TI, GLCT1, GLYT1, GNT-1, GNT-I, GnTI, MGAT, alpha-1 |
バックグラウンド: | There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1, 2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. |
UniProt Protein Function: | MGAT1: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. Belongs to the glycosyltransferase 13 family. |
UniProt Protein Details: | Protein type:EC 2.4.1.101; Glycan Metabolism - N-glycan biosynthesis; Membrane protein, integral; Transferase Chromosomal Location of Human Ortholog: 5q35.3 Cellular Component: Golgi membrane; membrane Molecular Function:acetylglucosaminyltransferase activity; alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity Biological Process: carbohydrate metabolic process |
NCBI Summary: | There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P26572 |
NCBI GenInfo Identifier: | 311033399 |
NCBI Gene ID: | 4245 |
NCBI Accession: | P26572.2 |
UniProt Secondary Accession: | P26572,Q6IBE3, A8K404, B3KRU8, D3DWR1, |
UniProt Related Accession: | P26572 |
Molecular Weight: | 51kDa |
NCBI Full Name: | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
NCBI Synonym Full Names: | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
NCBI Official Symbol: | MGAT1 |
NCBI Official Synonym Symbols: | GnTI; MGAT; GLCT1; GLYT1; GNT-1; GNT-I; GLCNAC-TI |
NCBI Protein Information: | alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
UniProt Protein Name: | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
UniProt Synonym Protein Names: | N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; GNT-I; GlcNAc-T I |
UniProt Gene Name: | MGAT1 |
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