Anti-MESDC2 Antibody (CAB13932)
- SKU:
- CAB13932
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-MESDC2 Antibody |
抗体コード: | CAB13932 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-234 of human MESDC2 (NP_055969.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | A-431, HepG2, SGC-7901, Mouse brain, Mouse heart, Rat heart |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-234 of human MESDC2 (NP_055969.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MAAS RWAR KAVV LLCA SDLL LLLL LLPP PGSC AAEG SPGT PDES TPPP RKKK KDIR DYND ADMA RLLE QWEK DDDI EEGD LPEH KRPS APVD FSKI DPSK PESI LKMT KKGK TLMM FVTV SGSP TEKE TEEI TSLW QGSL FNAN YDVQ RFIV GSDR AIFM LRDG SYAW EIKD FLVG QDRC ADVT LEGQ VYPG KGGG SKEK NKTK QDKG KKKK EGDL KSRS SKEE NRAG NKRE DL |
遺伝子ID: | 23184 |
Uniprot: | Q14696 |
セルラーロケーション: | Endoplasmic reticulum |
計算された分子量: | 26kDa |
観察された分子量: | 26kDa |
同義語: | MESDC2, BOCA, MESD |
バックグラウンド: |
UniProt Protein Function: | MESDC2: Chaperone specifically assisting the folding of beta- propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Monomer. Interacts with LRP5; the interaction prevents LRP5 from forming aggregates and chaperones LRP6 to the plasma membrane. Interacts with LRP6; the interaction prevents LRP6 from forming aggregates and chaperones LRP6 to the plasma membrane. Belongs to the MESD family. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 15q13 Biological Process: protein folding |
UniProt Code: | Q14696 |
NCBI GenInfo Identifier: | 24418861 |
NCBI Gene ID: | 23184 |
NCBI Accession: | Q14696.2 |
UniProt Secondary Accession: | Q14696,Q969U1, B4DW84, D3DW96, |
UniProt Related Accession: | Q14696 |
Molecular Weight: | 14,895 Da |
NCBI Full Name: | LDLR chaperone MESD |
NCBI Synonym Full Names: | mesoderm development candidate 2 |
NCBI Official Symbol: | MESDC2 |
NCBI Official Synonym Symbols: | BOCA; MESD |
NCBI Protein Information: | LDLR chaperone MESD |
UniProt Protein Name: | LDLR chaperone MESD |
UniProt Synonym Protein Names: | Mesoderm development candidate 2; Mesoderm development protein; Renal carcinoma antigen NY-REN-61 |
Protein Family: | LDLR chaperone |
UniProt Gene Name: | MESDC2 |
UniProt Entry Name: | MESD_HUMAN |
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