Anti-MED18 Antibody (CAB14588)
- SKU:
- CAB14588
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-MED18 Antibody |
抗体コード: | CAB14588 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-110 of human MED18 (NP_060108.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | HeLa |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-110 of human MED18 (NP_060108.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | HSLE SLIH RLRG LCDN MEPE TFLD HEMV FLLK GQQA SPFV LRAR RSMD RAGA PWHL RYLG QPEM GDKN RHAL VRNC VDIA T |
遺伝子ID: | 54797 |
Uniprot: | Q9BUE0 |
セルラーロケーション: | Nucleus |
計算された分子量: | 23kDa |
観察された分子量: | 24kDa |
同義語: | MED18, p28b, SRB5 |
バックグラウンド: |
UniProt Protein Function: | MED18: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Belongs to the Mediator complex subunit 18 family. |
UniProt Protein Details: | Protein type:Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 1p35.3 Cellular Component: Srb-mediator complex Molecular Function:protein binding Biological Process: termination of RNA polymerase II transcription |
NCBI Summary: | MED18 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008] |
UniProt Code: | Q9BUE0 |
NCBI GenInfo Identifier: | 74752353 |
NCBI Gene ID: | 54797 |
NCBI Accession: | Q9BUE0.1 |
UniProt Secondary Accession: | Q9BUE0,Q9NXU9, D3DPM1, |
UniProt Related Accession: | Q9BUE0 |
Molecular Weight: | 23,663 Da |
NCBI Full Name: | Mediator of RNA polymerase II transcription subunit 18 |
NCBI Synonym Full Names: | mediator complex subunit 18 |
NCBI Official Symbol: | MED18 |
NCBI Official Synonym Symbols: | p28b |
NCBI Protein Information: | mediator of RNA polymerase II transcription subunit 18 |
UniProt Protein Name: | Mediator of RNA polymerase II transcription subunit 18 |
UniProt Synonym Protein Names: | Mediator complex subunit 18; p28b |
Protein Family: | Mediator of RNA polymerase II transcription |
UniProt Gene Name: | MED18 |
UniProt Entry Name: | MED18_HUMAN |
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