Anti-MDH2 Antibody (CAB6297)
- SKU:
- CAB6297
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
抗体名: | Anti-MDH2 Antibody |
抗体コード: | CAB6297 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 59-338 of human MDH2 (NP_005909.2). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Jurkat, A-549, MCF7, HeLa, Mouse kidney, Mouse heart, Mouse skeletal muscle |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 59-338 of human MDH2 (NP_005909.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | AHTP GVAA DLSH IETK AAVK GYLG PEQL PDCL KGCD VVVI PAGV PRKP GMTR DDLF NTNA TIVA TLTA ACAQ HCPE AMIC VIAN PVNS TIPI TAEV FKKH GVYN PNKI FGVT TLDI VRAN TFVA ELKG LDPA RVNV PVIG GHAG KTII PLIS QCTP KVDF PQDQ LTAL TGRI QEAG TEVV KAKA GAGS ATLS MAYA GARF VFSL VDAM NGKE GVVE CSFV KSQE TECT YFST PLLL GKKG IEKN LGIG KVSS FEEK MISD AIPE LKAS IKKG EDFV KTLK |
遺伝子ID: | 4191 |
Uniprot: | P40926 |
セルラーロケーション: | Mitochondrion matrix |
計算された分子量: | 30kDa/35kDa |
観察された分子量: | 35kDa |
同義語: | MDH2, EIEE51, M-MDH, MDH, MGC:3559, MOR1 |
バックグラウンド: | Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | MDH2: mitochondrial malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. May play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. |
UniProt Protein Details: | Protein type:Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - citrate (TCA) cycle; Mitochondrial; Carbohydrate Metabolism - glyoxylate and dicarboxylate; EC 1.1.1.37; Oxidoreductase Chromosomal Location of Human Ortholog: 7cen-q22 Cellular Component: nucleoplasm; mitochondrion; mitochondrial matrix; mitochondrial inner membrane; plasma membrane; nucleus Molecular Function:protein self-association; L-malate dehydrogenase activity; malate dehydrogenase (NADP+) activity Biological Process: cellular metabolic process; malate metabolic process; oxaloacetate metabolic process; NADH metabolic process; tricarboxylic acid cycle; carbohydrate metabolic process; glucose metabolic process; pathogenesis; cellular carbohydrate metabolic process; internal protein amino acid acetylation; gluconeogenesis |
NCBI Summary: | Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] |
UniProt Code: | P40926 |
NCBI GenInfo Identifier: | 215274114 |
NCBI Gene ID: | 4191 |
NCBI Accession: | P40926.3 |
UniProt Secondary Accession: | P40926,O43682, A8K414, B2RE78, B4DE44, E9PDB2, |
UniProt Related Accession: | P40926 |
Molecular Weight: | 338 |
NCBI Full Name: | Malate dehydrogenase, mitochondrial |
NCBI Synonym Full Names: | malate dehydrogenase 2, NAD (mitochondrial) |
NCBI Official Symbol: | MDH2 |
NCBI Official Synonym Symbols: | MDH; MOR1; M-MDH; MGC:3559 |
NCBI Protein Information: | malate dehydrogenase, mitochondrial |
UniProt Protein Name: | Malate dehydrogenase, mitochondrial |
Protein Family: | Malate dehydrogenase |
UniProt Gene Name: | MDH2 |
UniProt Entry Name: | MDHM_HUMAN |