Anti-MARCO Antibody (CAB10048)
- SKU:
- CAB10048
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
抗体名: | Anti-MARCO Antibody |
抗体コード: | CAB10048 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 421-520 of human MARCO (NP_006761.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:1000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | A-549, K-562, Mouse spleen, Rat liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 421-520 of human MARCO (NP_006761.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | SVSV RIVG SSNR GRAE VYYS GTWG TICD DEWQ NSDA IVFC RMLG YSKG RALY KVGA GTGQ IWLD NVQC RGTE STLW SCTK NSWG HHDC SHEE DAGV ECSV |
遺伝子ID: | 8685 |
Uniprot: | Q9UEW3 |
セルラーロケーション: | Membrane, Single-pass type II membrane protein |
計算された分子量: | 43kDa/52kDa |
観察された分子量: | 60kDa |
同義語: | MARCO, SCARA2, SR-A6 |
バックグラウンド: | The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. |
UniProt Protein Function: | MARCO: Pattern recognition receptor (PRR). Binds Gram-positive and Gram-negative bacteria. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 2q14.2 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:pattern recognition receptor activity; transmembrane receptor activity Biological Process: cell surface receptor linked signal transduction; receptor-mediated endocytosis |
NCBI Summary: | The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UEW3 |
NCBI GenInfo Identifier: | 17380151 |
NCBI Gene ID: | 8685 |
NCBI Accession: | Q9UEW3.1 |
UniProt Secondary Accession: | Q9UEW3,Q9Y5S3, B4DW79, |
UniProt Related Accession: | Q9UEW3 |
Molecular Weight: | 43,865 Da |
NCBI Full Name: | Macrophage receptor MARCO |
NCBI Synonym Full Names: | macrophage receptor with collagenous structure |
NCBI Official Symbol: | MARCO |
NCBI Official Synonym Symbols: | SCARA2 |
NCBI Protein Information: | macrophage receptor MARCO |
UniProt Protein Name: | Macrophage receptor MARCO |
UniProt Synonym Protein Names: | Macrophage receptor with collagenous structure; Scavenger receptor class A member 2 |
Protein Family: | Macrophage receptor |
UniProt Gene Name: | MARCO |
UniProt Entry Name: | MARCO_HUMAN |
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