Anti-MAGT1 Antibody (CAB5039)
- SKU:
- CAB5039
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MAGT1
- Synonyms:
- IAP
- Synonyms:
- MRX95
- Synonyms:
- OST3B
- Synonyms:
- PRO0756
- Synonyms:
- XMEN
- Synonyms:
- bA217H1.1
Frequently bought together:
Description
| 抗体名: | MAGT1 Rabbit pAb |
| 抗体コード: | CAB5039 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | MAGT1, IAP, MRX95, OST3B, PRO0756, XMEN, bA217H1.1 |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-220 of human MAGT1 (NP_115497.4). |
| 申し込み: | WB |
| 推奨される希釈: | WB 1:500 - 1:1000 |
| 反応性: | Human |
| ポジティブサンプル: | U-251MG |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-220 of human MAGT1 (NP_115497.4). |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SAQR KKEM VLSE KVSQ LMEW TNKR PVIR MNGD KFRR LVKA PPRN YSVI VMFT ALQL HRQC VVCK QADE EFQI LANS WRYS SAFT NRIF FAMV DFDE GSDV FQML NMNS APTF INFP AKGK PKRG DTYE LQVR GFSA EQIA RWIA DRTD VNIR VIRP PNYA G |
| 遺伝子ID: | 84061 |
| Uniprot: | Q9H0U3 |
| セルラーロケーション: | Cell membrane, Endoplasmic reticulum membrane, Multi-pass membrane protein |
| 計算された分子量: | 15kDa/38kDa |
| 観察された分子量: | 50kDa |
| UniProt Protein Function: | MAGT1: May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells. Defects in MAGT1 are the cause of mental retardation X- linked type 95 (MRX95). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. In contrast to syndromic or specific X-linked mental retardation which also present with associated physical, neurological and/or psychiatric manifestations, intellectual deficiency is the only primary symptom of non-syndromic X-linked mental retardation. Defects in MAGT1 are the cause of immunodeficiency X- linked with magnesium defect Epstein-Barr virus infection and neoplasia (XMEN). XMEN is a disease characterized by CD4 lymphopenia, severe chronic viral infections, and defective T- lymphocyte activation. Belongs to the OST3/OST6 family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: Xq21.1 Cellular Component: membrane; oligosaccharyl transferase complex; plasma membrane Molecular Function:magnesium ion transmembrane transporter activity Biological Process: cognition; magnesium ion transport; protein amino acid N-linked glycosylation via asparagine; transmembrane transport Disease: Immunodeficiency, X-linked, With Magnesium Defect, Epstein-barr Virus Infection, And Neoplasia |
| NCBI Summary: | This gene encodes a magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause mental retardation X-linked type 95 (MRX95). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29. [provided by RefSeq, Jan 2010] |
| UniProt Code: | Q9H0U3 |
| NCBI GenInfo Identifier: | 74761391 |
| NCBI Gene ID: | 84061 |
| NCBI Accession: | Q9H0U3.1 |
| UniProt Secondary Accession: | Q9H0U3,Q53G00, Q6P577, Q8NBN6, B2RAR4, D3DTE3, |
| UniProt Related Accession: | Q9H0U3 |
| Molecular Weight: | 15,699 Da |
| NCBI Full Name: | Magnesium transporter protein 1 |
| NCBI Synonym Full Names: | magnesium transporter 1 |
| NCBI Official Symbol: | MAGT1 |
| NCBI Official Synonym Symbols: | IAP; XMEN; MRX95; OST3B; PRO0756; bA217H1.1 |
| NCBI Protein Information: | magnesium transporter protein 1 |
| UniProt Protein Name: | Magnesium transporter protein 1 |
| UniProt Synonym Protein Names: | Implantation-associated protein; IAP |
| Protein Family: | Magnesium transporter protein |
| UniProt Gene Name: | MAGT1 |
| UniProt Entry Name: | MAGT1_HUMAN |
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