Anti-MAF1 Antibody (CAB15531)
- SKU:
- CAB15531
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-MAF1 Antibody |
抗体コード: | CAB15531 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-256 of human MAF1 (NP_115648.2). |
申し込み: | WB |
推奨希釈: | WB 1:200 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | A-549, HeLa, Mouse thymus |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-256 of human MAF1 (NP_115648.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MKLL ENSS FEAI NSQL TVET GDAH IIGR IESY SCKM AGDD KHMF KQFC QEGQ PHVL EALS PPQT SGLS PSRL SKSQ GGEE EGPL SDKC SRKT LFYL IATL NESF RPDY DFST ARSH EFSR EPSL SWVV NAVN CSLF SAVR EDFK DLKP QLWN AVDE EICL AECD IYSY NPDL DSDP FGED GSLW SFNY FFYN KRLK RIVF FSCR SISG STYT PSEA GNEL DMEL GEEE VEEE SRSG GSGA EETS TMEE DRVP VICI |
遺伝子ID: | 84232 |
Uniprot: | Q9H063 |
セルラーロケーション: | Cytoplasm, Nucleus |
計算された分子量: | 28kDa |
観察された分子量: | 37kDa |
同義語: | MAF1, MAF1 homolog |
バックグラウンド: | This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. |
UniProt Protein Function: | MAF1: Element of the mTORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family. |
UniProt Protein Details: | Protein type:Transcription regulation Chromosomal Location of Human Ortholog: 8q24.3 Cellular Component: nucleoplasm; centrosome; intracellular membrane-bound organelle; axon; dendrite; cytoplasm; plasma membrane; nucleolus; intracellular; nucleus; cytosol Biological Process: transcription, DNA-dependent; negative regulation of transcription from RNA polymerase III promoter |
UniProt Code: | Q9H063 |
NCBI GenInfo Identifier: | 49065352 |
NCBI Gene ID: | |
NCBI Accession: | CAG38494.1 |
UniProt Secondary Accession: | Q9H063,D3DWL4, |
Molecular Weight: | 28,771 Da |
NCBI Full Name: | MAF1 |
UniProt Protein Name: | Repressor of RNA polymerase III transcription MAF1 homolog |
Protein Family: | Maf-like protein |
UniProt Gene Name: | MAF1 |
UniProt Entry Name: | MAF1_HUMAN |
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