Anti-LYRM1 Antibody (CAB15483)
- SKU:
- CAB15483
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-LYRM1 Antibody |
抗体コード: | CAB15483 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-122 of human LYRM1 (NP_065157.1). |
申し込み: | WB |
推奨希釈: | WB 1:200 - 1:2000 |
反応性: | Mouse |
ポジティブサンプル: | Mouse testis, Mouse brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-122 of human LYRM1 (NP_065157.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MTTA TRQE VLGL YRSI FRLA RKWQ ATSG QMED TIKE KQYI LNEA RTLF RKNK NLTD TDLI KQCI DECT ARIE IGLH YKIP YPRP IHLP PMGL TPLR GRGL RSQE KLRK LSKP VYLR SHDE VS |
遺伝子ID: | 57149 |
Uniprot: | O43325 |
セルラーロケーション: | Nucleus |
計算された分子量: | 14kDa |
観察された分子量: | 14kDa |
同義語: | LYRM1, A211C6.1 |
バックグラウンド: | The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | LYRM1: May promote cell proliferation and inhibition of apoptosis of preadipocytes. When overexpressed, may be involved in obesity- associated insulin resistance, possibly by causing mitochondrial dysfunction in adipocytes. Belongs to the complex I LYR family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 16p11.2 Cellular Component: nucleoplasm; intercellular bridge; mitochondrion |
NCBI Summary: | The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] |
UniProt Code: | O43325 |
NCBI GenInfo Identifier: | 119587248 |
NCBI Gene ID: | 57149 |
NCBI Accession: | EAW66844 |
UniProt Related Accession: | O43325 |
Molecular Weight: | 14 kDa |
NCBI Full Name: | hypothetical protein A-211C6.1, isoform CRA_b |
NCBI Synonym Full Names: | LYR motif containing 1 |
NCBI Official Symbol: | LYRM1 |
NCBI Official Synonym Symbols: | A211C6.1 |
NCBI Protein Information: | LYR motif-containing protein 1 |
UniProt Protein Name: | LYR motif-containing protein 1 |
Protein Family: | LYR motif containing protein |
UniProt Gene Name: | LYRM1 |
UniProt Entry Name: | LYRM1_HUMAN |
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