Anti-LTBR Antibody (CAB12006)
- SKU:
- CAB12006
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
抗体名: | Anti-LTBR Antibody |
抗体コード: | CAB12006 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 249-435 of human LTBR (NP_002333.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse |
ポジティブサンプル: | Mouse liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 249-435 of human LTBR (NP_002333.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | KSHP SLCR KLGS LLKR RPQG EGPN PVAG SWEP PKAH PYFP DLVQ PLLP ISGD VSPV STGL PAAP VLEA GVPQ QQSP LDLT REPQ LEPG EQSQ VAHG TNGI HVTG GSMT ITGN IYIY NGPV LGGP PGPG DLPA TPEP PYPI PEEG DPGP PGLS TPHQ EDGK AWHL AETE HCGA TPSN RGPR NQFI THD |
遺伝子ID: | 4055 |
Uniprot: | P36941 |
セルラーロケーション: | Membrane, Single-pass type I membrane protein |
計算された分子量: | 44kDa/46kDa |
観察された分子量: | 47kDa |
同義語: | LTBR, CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRSF3 |
バックグラウンド: | This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. |
UniProt Protein Function: | LTBR: Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 12p13 Cellular Component: integral to membrane Molecular Function:identical protein binding; protein binding; ubiquitin protein ligase binding Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; viral reproduction; apoptosis; positive regulation of JNK cascade; myeloid dendritic cell differentiation; signal transduction |
NCBI Summary: | This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012] |
UniProt Code: | P36941 |
NCBI GenInfo Identifier: | 549090 |
NCBI Gene ID: | 4055 |
NCBI Accession: | P36941.1 |
UniProt Secondary Accession: | P36941,B7Z1D2, D3DUR2, F5GXE7, |
UniProt Related Accession: | P36941 |
Molecular Weight: | 435 |
NCBI Full Name: | Tumor necrosis factor receptor superfamily member 3 |
NCBI Synonym Full Names: | lymphotoxin beta receptor (TNFR superfamily, member 3) |
NCBI Official Symbol: | LTBR |
NCBI Official Synonym Symbols: | CD18; TNFCR; TNFR3; D12S370; TNFR-RP; TNFRSF3; TNFR2-RP; LT-BETA-R; TNF-R-III |
NCBI Protein Information: | tumor necrosis factor receptor superfamily member 3; lymphotoxin B receptor; tumor necrosis factor C receptor; tumor necrosis factor receptor type III; tumor necrosis factor receptor 2-related protein |
UniProt Protein Name: | Tumor necrosis factor receptor superfamily member 3 |
UniProt Synonym Protein Names: | Lymphotoxin-beta receptor; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor type III; TNF-RIII; TNFR-III |
Protein Family: | Tumor necrosis factor receptor superfamily |
UniProt Gene Name: | LTBR |
UniProt Entry Name: | TNR3_HUMAN |
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