Anti-LSS Antibody (CAB6930)
- SKU:
- CAB6930
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-LSS Antibody |
抗体コード: | CAB6930 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human LSS (NP_002331.3). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | BT-474, Mouse lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human LSS (NP_002331.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MTEG TCLR RRGG PYKT EPAT DLGR WRLN CERG RQTW TYLQ DERA GREQ TGLE AYAL GLDT KNYF KDLP KAHT AFEG ALNG MTFY VGLQ AEDG HWTG DYGG PLFL LPGL LITC HVAR IPLP AGYR EEIV RYLR SVQL PDGG WGLH IEDK STVF GTAL NYVS LRIL GVGP DDPD LVRA RNIL HKKG GAVA IPSW GKFW LAVL NVYS WEGL NTLF PEMW LFPD WAPA HPST LWCH CRQV YLPM SYCY AVRL SAAE DPLV QSLR QELY VEDF ASID WLAQ RNNV APDE LYTP HSWL LRVV YALL |
遺伝子ID: | 4047 |
Uniprot: | P48449 |
セルラーロケーション: | Endoplasmic reticulum membrane, Peripheral membrane protein |
計算された分子量: | 74kDa/82kDa/83kDa |
観察された分子量: | 75kDa |
同義語: | LSS, CTRCT44, OSC |
バックグラウンド: | The protein encoded by this gene catalyzes the conversion of (S)-2, 3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms. |
UniProt Protein Function: | LSS: Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Belongs to the terpene cyclase/mutase family. |
UniProt Protein Details: | Protein type:Lipid Metabolism - steroid biosynthesis; EC 5.4.99.7; Isomerase Chromosomal Location of Human Ortholog: 21q22.3 Cellular Component: endoplasmic reticulum membrane; membrane; lipid particle Molecular Function:lanosterol synthase activity Biological Process: steroid metabolic process; cholesterol biosynthetic process Disease: Cataract 44 |
NCBI Summary: | The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009] |
UniProt Code: | P48449 |
NCBI GenInfo Identifier: | 1352387 |
NCBI Gene ID: | 4047 |
NCBI Accession: | P48449.1 |
UniProt Secondary Accession: | P48449,Q8IYL6, Q9UEZ1, B4DJZ9, D3DSN0, E9PEI9, G5E9Q9 |
UniProt Related Accession: | P48449 |
Molecular Weight: | 82,199 Da |
NCBI Full Name: | Lanosterol synthase |
NCBI Synonym Full Names: | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
NCBI Official Symbol: | LSS |
NCBI Official Synonym Symbols: | OSC |
NCBI Protein Information: | lanosterol synthase; hOSC; oxidosqualene--lanosterol cyclase; 2,3-epoxysqualene-lanosterol cyclase; 2,3-epoxysqualene--lanosterol cyclase |
UniProt Protein Name: | Lanosterol synthase |
UniProt Synonym Protein Names: | 2,3-epoxysqualene--lanosterol cyclase; Oxidosqualene--lanosterol cyclase; OSC; hOSC |
Protein Family: | Lysostaphin |
UniProt Gene Name: | LSS |
UniProt Entry Name: | ERG7_HUMAN |
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