Anti-LHX1 Antibody (CAB17344)
- SKU:
- CAB17344
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Description
抗体名: | Anti-LHX1 Antibody |
抗体コード: | CAB17344 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-180 of human LHX1 (NP_005559.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-87MG, Mouse testis, Mouse brain, Rat testis, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-180 of human LHX1 (NP_005559.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | SNSS VAKE NSLH SATT GSDP SLSP DSQD PSQD DAKD SESA NVSD KEAG SNEN DDQN LGAK R |
遺伝子ID: | 3975 |
Uniprot: | P48742 |
セルラーロケーション: | Nucleus |
計算された分子量: | 44kDa |
観察された分子量: | 52kDa |
同義語: | LHX1, LIM-1, LIM1 |
バックグラウンド: | This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor important for the development of the renal and urogenital systems. This gene is a candidate for Mayer-Rokitansky-Kuster-Hauser syndrome, a disorder characterized by anomalies in the female genital tract. |
UniProt Protein Function: | LHX1: Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis. |
UniProt Protein Details: | Protein type:Transcription factor; Cell development/differentiation Chromosomal Location of Human Ortholog: 17q12 Cellular Component: protein complex; nucleus Molecular Function:zinc ion binding; sequence-specific DNA binding; transcription corepressor activity; transcription factor activity Biological Process: transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; motor axon guidance; uterus development; forebrain regionalization; embryonic pattern specification; pronephros development; post-embryonic development; anterior/posterior pattern formation; cell-cell signaling; ectoderm formation; ureteric bud development; anatomical structure formation; cerebellum development; kidney development; fallopian tube development; cervix development; nervous system development; anatomical structure morphogenesis; vagina development; ventral spinal cord development; gastrulation with mouth forming second; embryonic viscerocranium morphogenesis; somite rostral/caudal axis specification; pattern specification process; Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation; organ morphogenesis; telencephalon development; positive regulation of embryonic development; dorsal/ventral pattern formation; regulation of gene expression; endoderm formation; ureteric bud branching; embryonic retina morphogenesis in camera-type eye; cerebellar Purkinje cell differentiation; spinal cord association neuron differentiation; negative regulation of transcription, DNA-dependent; urogenital system development; anterior/posterior axis specification |
NCBI Summary: | This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor important for the development of the renal and urogenital systems. This gene is a candidate for Mayer-Rokitansky-Kuster-Hauser syndrome, a disorder characterized by anomalies in the female genital tract. [provided by RefSeq, Dec 2010] |
UniProt Code: | P48742 |
NCBI GenInfo Identifier: | 30410785 |
NCBI Gene ID: | 3975 |
NCBI Accession: | NP_005559 |
UniProt Related Accession: | P48742 |
Molecular Weight: | 45kDa |
NCBI Full Name: | LIM/homeobox protein Lhx1 |
NCBI Synonym Full Names: | LIM homeobox 1 |
NCBI Official Symbol: | LHX1 |
NCBI Official Synonym Symbols: | LIM1; LIM-1 |
NCBI Protein Information: | LIM/homeobox protein Lhx1 |
UniProt Protein Name: | LIM/homeobox protein Lhx1 |
UniProt Synonym Protein Names: | Homeobox protein Lim-1 |
UniProt Gene Name: | LHX1 |
UniProt Entry Name: | LHX1_HUMAN |