Anti-KLHL15 Antibody (CAB16574)
- SKU:
- CAB16574
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-KLHL15 Antibody |
抗体コード: | CAB16574 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human KLHL15 (NP_085127.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | 293T, U-251MG, Mouse brain, Mouse lung, Rat lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human KLHL15 (NP_085127.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MAGD VEGF CSSI HDTS VSAG FRAL YEEG LLLD VTLV IEDH QFQA HKAL LATQ SDYF RIMF TADM RERD QDKI HLKG LTAT GFSH VLQF MYYG TIEL SMNT VHEI LQAA MYVQ LIEV VKFC CSFL LAKI CLEN CAEI MRLL DDFG VNIE GVRE KLDT FLLD NFVP LMSR PDFL SYLS FEKL MSYL DNDH LSRF PEIE LYEA VQSW LRHD RRRW RHTD TIIQ NIRF CLMT PTSV FEKV KTSE FYRY SRQL RYEV DQAL NYFQ NVHQ QPLL DMKS SRIR SAKP QTTV FRGM IGHS MVNS KILL |
遺伝子ID: | 80311 |
Uniprot: | Q96M94 |
セルラーロケーション: | |
計算された分子量: | 69kDa |
観察された分子量: | 70kDa |
同義語: | KLHL15, HEL-S-305 |
バックグラウンド: | This gene encodes a member of the kelch-like family of proteins that share a common domain structure consisting of an N-terminal broad-complex, tramtrack, bric-a-brac/poxvirus and zinc finger domain and C-terminal kelch repeat motifs. The encoded protein may be involved in protein ubiquitination and cytoskeletal organization. |
UniProt Protein Function: | KLHL15: a substrate-specific adapter for the recruitment of substrates to Cul3-based E3 ubiquitin ligases. KLHL15-Cul3 specifically targets the PP2A regulatory subunit PPP2R5B to promote its turnover by ubiquitylation and proteasomal degradation. May contribute to the selective expression of the PP2A/B holoenzyme in the brain. |
UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: Xp22.1-p21 Biological Process: protein ubiquitination |
UniProt Code: | Q96M94 |
NCBI GenInfo Identifier: | 226442729 |
NCBI Gene ID: | |
NCBI Accession: | NP_085127 |
Molecular Weight: | 70kDa |
NCBI Full Name: | kelch-like protein 15 |
UniProt Protein Name: | Kelch-like protein 15 |
Protein Family: | Kelch-like protein |
UniProt Gene Name: | KLHL15 |
UniProt Entry Name: | KLH15_HUMAN |
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