Anti-KLF7 Antibody (CAB8879)
- SKU:
- CAB8879
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-KLF7 Antibody |
抗体コード: | CAB8879 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 51-230 of human KLF7 (NP_001257871.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | 293T, 22Rv1, K-562, Mouse kidney |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 51-230 of human KLF7 (NP_001257871.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | SETF GEDL DCFL HASP PPCI EESF RRLD PLLL PVEA AICE KSSA VDIL LSRD KLLS ETCL SLQP ASSS LDSY TAVN QAQL NAVT SLTP PSSP ELSR HLVK TSQT LSAV DGTV TLKL VAKK AALS SVKV RSLI SAHG RDVS GVLH EAMS SRGT TGNT QVQS PSNA TTAT GVFP GLTI LPST |
遺伝子ID: | 8609 |
Uniprot: | O75840 |
セルラーロケーション: | Nucleus |
計算された分子量: | 9kDa/13kDa/24kDa/29kDa/30kDa/33kDa |
観察された分子量: | 37kDa |
同義語: | KLF7, UKLF |
バックグラウンド: | The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | KLF7: Transcriptional activator. Binds in vitro to the CACCC motif of the beta-globin promoter and to the SP1 recognition sequence. Belongs to the krueppel C2H2-type zinc-finger protein family. |
UniProt Protein Details: | Protein type:DNA-binding; C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: 2q32 Cellular Component: nucleus Molecular Function:DNA binding; zinc ion binding; transcription coactivator activity; transcription factor activity Biological Process: regulation of transcription from RNA polymerase II promoter; axon guidance; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; dendrite morphogenesis |
NCBI Summary: | The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |
UniProt Code: | O75840 |
NCBI GenInfo Identifier: | 401709918 |
NCBI Gene ID: | 8609 |
NCBI Accession: | NP_001257871.1 |
UniProt Secondary Accession: | O75840,Q7Z3H8, Q96E51, B2RB03, B7Z4F7, C9JF04, E7EWH1 L0R4P2, |
UniProt Related Accession: | O75840 |
Molecular Weight: | 33kd |
NCBI Full Name: | Krueppel-like factor 7 isoform 2 |
NCBI Synonym Full Names: | Kruppel-like factor 7 (ubiquitous) |
NCBI Official Symbol: | KLF7 |
NCBI Official Synonym Symbols: | UKLF |
NCBI Protein Information: | Krueppel-like factor 7 |
UniProt Protein Name: | Krueppel-like factor 7 |
UniProt Synonym Protein Names: | Ubiquitous krueppel-like factor |
Protein Family: | Krueppel-like factor |
UniProt Gene Name: | KLF7 |
UniProt Entry Name: | KLF7_HUMAN |
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