Anti-KIF5C Antibody (CAB13801)
- SKU:
- CAB13801
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-KIF5C Antibody |
抗体コード: | CAB13801 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 510-590 of human KIF5C (NP_004513.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | HT-29, OVCAR3 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 510-590 of human KIF5C (NP_004513.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | RANE QLTD ELAQ KTTT LTTT QREL SQLQ ELSN HQKK RATE ILNL LLKD LGEI GGII GTND VKTL ADVN GVIE EEFT MARL Y |
遺伝子ID: | 3800 |
Uniprot: | O60282 |
セルラーロケーション: | Cytoplasm, cytoskeleton |
計算された分子量: | 83kDa/109kDa |
観察された分子量: | 109kDa |
同義語: | KIF5C, CDCBM2, KINN, NKHC, NKHC-2, NKHC2 |
バックグラウンド: | The protein encoded by this gene is a kinesin heavy chain subunit involved in the transport of cargo within the central nervous system. The encoded protein, which acts as a tetramer by associating with another heavy chain and two light chains, interacts with protein kinase CK2. Mutations in this gene have been associated with complex cortical dysplasia with other brain malformations-2. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. |
UniProt Protein Function: | KIF5C: Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Belongs to the kinesin-like protein family. Kinesin subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 2q23.1 Cellular Component: kinesin complex Molecular Function:microtubule motor activity; plus-end-directed microtubule motor activity; protein binding Biological Process: axon guidance; cytoskeleton-dependent intracellular transport; microtubule-based movement; mRNA transport; organelle organization and biogenesis; protein localization Disease: Cortical Dysplasia, Complex, With Other Brain Malformations 2 |
NCBI Summary: | The protein encoded by this gene is a kinesin heavy chain subunit involved in the transport of cargo within the central nervous system. The encoded protein, which acts as a tetramer by associating with another heavy chain and two light chains, interacts with protein kinase CK2. Mutations in this gene have been associated with complex cortical dysplasia with other brain malformations-2. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Jul 2015] |
UniProt Code: | O60282 |
NCBI GenInfo Identifier: | 13124319 |
NCBI Gene ID: | 3800 |
NCBI Accession: | O60282.1 |
UniProt Secondary Accession: | O60282,O95079, Q2YDC5, |
UniProt Related Accession: | O60282 |
Molecular Weight: | 83,178 Da |
NCBI Full Name: | Kinesin heavy chain isoform 5C |
NCBI Synonym Full Names: | kinesin family member 5C |
NCBI Official Symbol: | KIF5C |
NCBI Official Synonym Symbols: | KINN; NKHC; NKHC2; CDCBM2; NKHC-2 |
NCBI Protein Information: | kinesin heavy chain isoform 5C |
UniProt Protein Name: | Kinesin heavy chain isoform 5C |
UniProt Synonym Protein Names: | Kinesin heavy chain neuron-specific 2 |
Protein Family: | Kinesin |
UniProt Gene Name: | KIF5C |
UniProt Entry Name: | KIF5C_HUMAN |
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