Anti-ISG20 Antibody (CAB14744)
- SKU:
- CAB14744
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
抗体名: | Anti-ISG20 Antibody |
抗体コード: | CAB14744 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human ISG20 (NP_002192.2). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Raji, A-549, MCF7, Mouse spleen, Rat spleen |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human ISG20 (NP_002192.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MAGS REVV AMDC EMVG LGPH RESG LARC SLVN VHGA VLYD KFIR PEGE ITDY RTRV SGVT PQHM VGAT PF |
遺伝子ID: | 3669 |
Uniprot: | Q96AZ6 |
セルラーロケーション: | Cajal body, Cytoplasm, Nucleus, nucleolus |
計算された分子量: | 9kDa/20kDa |
観察された分子量: | 20kDa |
同義語: | ISG20, CD25, HEM45 |
バックグラウンド: |
UniProt Protein Function: | ISG20: Exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. Degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. Involved in the antiviral function of IFN against RNA viruses. Belongs to the exonuclease superfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Nucleolus; Ribonuclease; Deoxyribonuclease; EC 3.1.13.1 Chromosomal Location of Human Ortholog: 15q26 Cellular Component: Cajal body; cytoplasm; nucleolus; nucleoplasm; nucleus; PML body Molecular Function:3'-5'-exoribonuclease activity; exonuclease activity; single-stranded DNA specific 3'-5' exodeoxyribonuclease activity; U1 snRNA binding; U2 snRNA binding Biological Process: cell proliferation; defense response to virus; DNA catabolic process, exonucleolytic; negative regulation of viral genome replication; response to virus; RNA catabolic process |
UniProt Code: | Q96AZ6 |
NCBI GenInfo Identifier: | 57012967 |
NCBI Gene ID: | 3669 |
NCBI Accession: | Q96AZ6.2 |
UniProt Secondary Accession: | Q96AZ6,O00441, O00586, |
UniProt Related Accession: | Q96AZ6 |
Molecular Weight: | 9,199 Da |
NCBI Full Name: | Interferon-stimulated gene 20 kDa protein |
NCBI Synonym Full Names: | interferon stimulated exonuclease gene 20 |
NCBI Official Symbol: | ISG20 |
NCBI Official Synonym Symbols: | CD25; HEM45 |
NCBI Protein Information: | interferon-stimulated gene 20 kDa protein |
UniProt Protein Name: | Interferon-stimulated gene 20 kDa protein |
UniProt Synonym Protein Names: | Estrogen-regulated transcript 45 protein; Promyelocytic leukemia nuclear body-associated protein ISG20 |
Protein Family: | Interferon-stimulated gene 20 kDa protein |
UniProt Gene Name: | ISG20 |
UniProt Entry Name: | ISG20_HUMAN |
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