Anti-IDI2 Antibody (CAB14434)
- SKU:
- CAB14434
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-IDI2 Antibody |
抗体コード: | CAB14434 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-180 of human IDI2 (NP_150286.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | 293T |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-180 of human IDI2 (NP_150286.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | NTKN RILI QQRS DTKV TFPG YFTD SCSS HPLY NPAE LEEK DAIG VRRA AQRR LQAE LGIP GEQI SPED IVFM TIYH HKAK SDRI WGEH EICY LLLV RKNV TLNP DPSE TKSI LYLS QEEL W |
遺伝子ID: | 91734 |
Uniprot: | Q9BXS1 |
セルラーロケーション: | Peroxisome |
計算された分子量: | 26kDa |
観察された分子量: | 27kDa |
同義語: | IDI2, IPPI2 |
バックグラウンド: | The protein encoded by this gene catalyzes the conversion of isopentenyl diphosphate to dimethylallyl diphosphate, which is a precursor for the synthesis of cholesterol and other isoprenoids. This gene, which is a product of an ancestral gene duplication event, encodes a protein that may be involved in the aggregation of alpha-synuclein in the cerebral cortex of patients with Lewy body disease. In addition, segmental copy number gains in this locus have been associated with sporadic amyotrophic lateral sclerosis. |
UniProt Protein Function: | IDI2: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). Belongs to the IPP isomerase type 1 family. |
UniProt Protein Details: | Protein type:Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; EC 5.3.3.2; Isomerase Chromosomal Location of Human Ortholog: 10p15.3 Cellular Component: peroxisome; cytosol Molecular Function:hydrolase activity; metal ion binding; isopentenyl-diphosphate delta-isomerase activity Biological Process: isoprenoid biosynthetic process; isopentenyl diphosphate metabolic process; dimethylallyl diphosphate biosynthetic process; cholesterol biosynthetic process |
UniProt Code: | Q9BXS1 |
NCBI GenInfo Identifier: | 15147242 |
NCBI Gene ID: | 91734 |
NCBI Accession: | NP_150286.1 |
UniProt Related Accession: | Q9BXS1 |
Molecular Weight: | 26,753 Da |
NCBI Full Name: | isopentenyl-diphosphate delta-isomerase 2 |
NCBI Synonym Full Names: | isopentenyl-diphosphate delta isomerase 2 |
NCBI Official Symbol: | IDI2 |
NCBI Official Synonym Symbols: | IPPI2 |
NCBI Protein Information: | isopentenyl-diphosphate delta-isomerase 2; IPP isomerase 2; diphosphate dimethylallyl diphosphate isomerase 2; isopentenyl pyrophosphate isomerase 2; isopentenyl-diphosphate Delta-isomerase 2 |
UniProt Protein Name: | Isopentenyl-diphosphate delta-isomerase 2 |
UniProt Synonym Protein Names: | Isopentenyl pyrophosphate isomerase 2; IPP isomerase 2; IPPI2 |
Protein Family: | Isopentenyl-diphosphate Delta-isomerase |
UniProt Gene Name: | IDI2 |
UniProt Entry Name: | IDI2_HUMAN |
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