Anti-HTATSF1 Antibody (CAB5977)
- SKU:
- CAB5977
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-HTATSF1 Antibody |
抗体コード: | CAB5977 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human HTATSF1 (NP_055315.2). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:1000 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-251MG, Jurkat, HepG2 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human HTATSF1 (NP_055315.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MSGT NLDG NDEF DEQL RMQE LYGD GKDG DTQT DAGG EPDS LGQQ PTDT PYEW DLDK KAWF PKIT EDFI ATYQ ANYG FSND GASS STAN VEDV HART AEEP PQEK APEP TDAR KKGE KRKA ESGW FHVE EDRN TNVY VSGL PPDI TVDE FIQL MSKF GIIM RDPQ TEEF KVKL YKDN QGNL KGDG LCCY LKRE SVEL ALKL LDED EIRG YKLH VEVA KFQL KGEY DASK KKKK CKDY KKKL SMQQ KQLD WRPE RRAG PSRM RHER VVII KN |
遺伝子ID: | 27336 |
Uniprot: | O43719 |
セルラーロケーション: | Nucleus |
計算された分子量: | 85kDa |
観察された分子量: | 129kDa |
同義語: | HTATSF1, TAT-SF1, TATSF1, dJ196E23.2 |
バックグラウンド: | The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene. |
UniProt Protein Function: | TAT-SF1: Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor required for the Tat-enhanced transcription of the virus. Belongs to the HTATSF1 family. |
UniProt Protein Details: | Protein type:Spliceosome; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: Xq26.3 Cellular Component: nucleoplasm; nucleus Molecular Function:nucleotide binding Biological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; viral genome replication; regulation of RNA elongation |
NCBI Summary: | The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Sep 2009] |
UniProt Code: | O43719 |
NCBI GenInfo Identifier: | 74754346 |
NCBI Gene ID: | 27336 |
NCBI Accession: | O43719.1 |
UniProt Secondary Accession: | O43719,Q59G06, Q99730, D3DWG9, |
UniProt Related Accession: | O43719 |
Molecular Weight: | 85,853 Da |
NCBI Full Name: | HIV Tat-specific factor 1 |
NCBI Synonym Full Names: | HIV-1 Tat specific factor 1 |
NCBI Official Symbol: | HTATSF1 |
NCBI Official Synonym Symbols: | TATSF1; TAT-SF1; dJ196E23.2 |
NCBI Protein Information: | HIV Tat-specific factor 1; HIV TAT specific factor 1; cofactor required for Tat activation of HIV-1 transcription |
UniProt Protein Name: | HIV Tat-specific factor 1 |
Protein Family: | HIV Tat-specific factor |
UniProt Gene Name: | HTATSF1 |
UniProt Entry Name: | HTSF1_HUMAN |
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