Anti-HSD17B1 Antibody (CAB10839)
- SKU:
- CAB10839
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-HSD17B1 Antibody |
抗体コード: | CAB10839 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-328 of human HSD17B1 (NP_000404.2). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-87MG, Rat ovary |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-328 of human HSD17B1 (NP_000404.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MART VVLI TGCS SGIG LHLA VRLA SDPS QSFK VYAT LRDL KTQG RLWE AARA LACP PGSL ETLQ LDVR DSKS VAAA RERV TEGR VDVL VCNA GLGL LGPL EALG EDAV ASVL DVNV VGTV RMLQ AFLP DMKR RGSG RVLV TGSV GGLM GLPF NDVY CASK FALE GLCE SLAV LLLP FGVH LSLI ECGP VHTA FMEK VLGS PEEV LDRT DIHT FHRF YQYL AHSK QVFR EAAQ NPEE VAEV FLTA LRAP KPTL RYFT TERF LPLL RMRL DDPS GSNY VTAM HREV FGDV PAKA EAGA EAGG GAGP GAED EAGR GAVG DPEL GDPP AAPQ |
遺伝子ID: | 3292 |
Uniprot: | P14061 |
セルラーロケーション: | Cytoplasm |
計算された分子量: | 34kDa |
観察された分子量: | 35kDa |
同義語: | HSD17B1, 17-beta-HSD, 20-alpha-HSD, E2DH, EDH17B2, EDHB17, HSD17, SDR28C1 |
バックグラウンド: |
UniProt Protein Function: | HSD17B1: Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH. Belongs to the short-chain dehydrogenases/reductases (SDR) family. |
UniProt Protein Details: | Protein type:Lipid Metabolism - androgen and estrogen; EC 1.1.1.62; Oxidoreductase Chromosomal Location of Human Ortholog: 17q11-q21 Cellular Component: nucleoplasm; nuclear membrane; cytoplasm; cytosol Molecular Function:estradiol 17-beta-dehydrogenase activity; catalytic activity; 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity Biological Process: steroid metabolic process; estrogen metabolic process; steroid biosynthetic process; estrogen biosynthetic process |
UniProt Code: | P14061 |
NCBI GenInfo Identifier: | 313104233 |
NCBI Gene ID: | 3292 |
NCBI Accession: | P14061.3 |
UniProt Secondary Accession: | P14061,Q2M2L8, B3KXS1, |
UniProt Related Accession: | P14061 |
Molecular Weight: | 34,950 Da |
NCBI Full Name: | Estradiol 17-beta-dehydrogenase 1 |
NCBI Synonym Full Names: | hydroxysteroid (17-beta) dehydrogenase 1 |
NCBI Official Symbol: | HSD17B1 |
NCBI Official Synonym Symbols: | HSD17; EDHB17; EDH17B2; SDR28C1 |
NCBI Protein Information: | estradiol 17-beta-dehydrogenase 1; E2DH; 20-alpha-HSD; 17-beta-HSD 1; estradiol 17-beta-dehydrogenase-1; 20 alpha-hydroxysteroid dehydrogenase; 17-beta-hydroxysteroid dehydrogenase type 1; placental 17-beta-hydroxysteroid dehydrogenase; hydroxysteroid (17-beta) dehydrogenase 1 isoform; short chain dehydrogenase/reductase family 28CE, member 1 |
UniProt Protein Name: | Estradiol 17-beta-dehydrogenase 1 |
UniProt Synonym Protein Names: | 17-beta-hydroxysteroid dehydrogenase type 1; 17-beta-HSD 1; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; E2DH; Placental 17-beta-hydroxysteroid dehydrogenase |
Protein Family: | Estradiol 17-beta-dehydrogenase |
UniProt Gene Name: | HSD17B1 |
UniProt Entry Name: | DHB1_HUMAN |
View AllClose