Anti-HMGN2 Antibody (CAB6156)
- SKU:
- CAB6156
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-HMGN2 Antibody |
抗体コード: | CAB6156 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human HMGN2 (NP_005508.1). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
反応性: | Human |
ポジティブサンプル: | 293T, HepG2, MCF7 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human HMGN2 (NP_005508.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MPKR KAEG DAKG DKAK VKDE PQRR SARL SAKP APPK PEPK PKKA PAKK GEKV PKGK KGKA DAGK EGNN PAEN GDAK TDQA QKAE GAGD AK |
遺伝子ID: | 3151 |
Uniprot: | P05204 |
セルラーロケーション: | Cytoplasm, Nucleus |
計算された分子量: | 9kDa |
観察された分子量: | 17kDa |
同義語: | HMGN2, HMG17 |
バックグラウンド: | The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. |
UniProt Protein Function: | HMGN2: Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation. Belongs to the HMGN family. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 1p36.1 Cellular Component: cytoplasm; nucleus; chromatin Molecular Function:nucleosomal DNA binding |
NCBI Summary: | The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. [provided by RefSeq, Oct 2014] |
UniProt Code: | P05204 |
NCBI GenInfo Identifier: | 123106 |
NCBI Gene ID: | 3151 |
NCBI Accession: | P05204.3 |
UniProt Secondary Accession: | P05204,Q0VGD5, Q6FGI5, Q96C64, |
UniProt Related Accession: | P05204 |
Molecular Weight: | 90 |
NCBI Full Name: | Non-histone chromosomal protein HMG-17 |
NCBI Synonym Full Names: | high mobility group nucleosomal binding domain 2 |
NCBI Official Symbol: | HMGN2 |
NCBI Official Synonym Symbols: | HMG17 |
NCBI Protein Information: | non-histone chromosomal protein HMG-17; high mobility group protein N2; nonhistone chromosomal protein HMG-17; high-mobility group nucleosomal binding domain 2; high-mobility group (nonhistone chromosomal) protein 17; high mobility group nucleosome-binding domain-containing protein 2 |
UniProt Protein Name: | Non-histone chromosomal protein HMG-17 |
UniProt Synonym Protein Names: | High mobility group nucleosome-binding domain-containing protein 2 |
Protein Family: | Non-histone chromosomal protein |
UniProt Gene Name: | HMGN2 |
UniProt Entry Name: | HMGN2_HUMAN |
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