Anti-HDAC11 Antibody (CAB6140)
- SKU:
- CAB6140
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-HDAC11 Antibody |
抗体コード: | CAB6140 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-347 of human HDAC11 (NP_079103.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Mouse small intestine, BT-474, MCF7, Mouse brain, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-347 of human HDAC11 (NP_079103.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | GLSI SPAG IVKR DELV FRMV RGRR VPIL MVTS GGYQ KRTA RIIA DSIL NLFG LGLI GPES PSVS AQNS DTPL LPPA VP |
遺伝子ID: | 79885 |
Uniprot: | Q96DB2 |
セルラーロケーション: | Nucleus |
計算された分子量: | 33kDa/39kDa |
観察された分子量: | 39kDa |
同義語: | HDAC11, HD11 |
バックグラウンド: | This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | HDAC11: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Belongs to the histone deacetylase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.5.1.98; Deacetylase Chromosomal Location of Human Ortholog: 3p25.1 Cellular Component: histone deacetylase complex; nucleus; plasma membrane Molecular Function:histone deacetylase activity; transcription factor binding Biological Process: chromatin modification; histone deacetylation |
NCBI Summary: | This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2009] |
UniProt Code: | Q96DB2 |
NCBI GenInfo Identifier: | 26394832 |
NCBI Gene ID: | 79885 |
NCBI Accession: | Q96DB2.1 |
UniProt Secondary Accession: | Q96DB2,Q9H6I7, Q9H6X3, Q9NTC9, B4DDK1, |
UniProt Related Accession: | Q96DB2 |
Molecular Weight: | 33,124 Da |
NCBI Full Name: | Histone deacetylase 11 |
NCBI Synonym Full Names: | histone deacetylase 11 |
NCBI Official Symbol: | HDAC11 |
NCBI Official Synonym Symbols: | HD11 |
NCBI Protein Information: | histone deacetylase 11 |
UniProt Protein Name: | Histone deacetylase 11 |
Protein Family: | Histone deacetylase |
UniProt Gene Name: | HDAC11 |
UniProt Entry Name: | HDA11_HUMAN |
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