Anti-HBS1L Antibody (CAB10037)
- SKU:
- CAB10037
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-HBS1L Antibody |
抗体コード: | CAB10037 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human HBS1L (NP_006611.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:1000 |
反応性: | Human, Mouse |
ポジティブサンプル: | NIH/3T3, Mouse pancreas |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human HBS1L (NP_006611.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MARH RNVR GYNY DEDF EDDD LYGQ SVED DYCI SPST AAQF IYSR RDKP SVEP VEEY DYED LKES SNSV SNHQ LSGF DQAR LYSC LDHM REVL GDAV PDEI LIEA VLKN KFDV QKAL SGVL EQDR VQSL KDKN EATV STGK IAKG KPVD SQTS RSES EIVP KVAK MTVS GKKQ TMGF EVPG VSSE ENGH SFHT PQKG PPIE DAIA SSDV LETA SKSA NPPH TIQA SEEQ SSTP APVK KSGK LRQQ IDVK AELE KRQG GKQL |
遺伝子ID: | 10767 |
Uniprot: | Q9Y450 |
セルラーロケーション: | |
計算された分子量: | 70kDa/75kDa |
観察された分子量: | 75kDa |
同義語: | HBS1L, EF-1a, ERFS, HBS1, HSPC276, eRF3c |
バックグラウンド: | This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. |
UniProt Protein Function: | HBS1: a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, May 2009] |
UniProt Protein Details: | Protein type:Translation; Translation elongation; RNA-binding Chromosomal Location of Human Ortholog: 6q23.3 Cellular Component: intracellular; membrane Molecular Function:GTPase activity Biological Process: ribosome disassembly; signal transduction; translation |
NCBI Summary: | This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, May 2009] |
UniProt Code: | Q9Y450 |
NCBI GenInfo Identifier: | 68566500 |
NCBI Gene ID: | 10767 |
NCBI Accession: | Q9Y450.1 |
UniProt Secondary Accession: | Q9Y450,Q4VX89, Q4VX90, Q5T7G3, Q8NDW9, Q9UPW3, B7Z365 |
UniProt Related Accession: | Q9Y450 |
Molecular Weight: | 70,625 Da |
NCBI Full Name: | HBS1-like protein |
NCBI Synonym Full Names: | HBS1 like translational GTPase |
NCBI Official Symbol: | HBS1L |
NCBI Official Synonym Symbols: | ERFS; HBS1; EF-1a; eRF3c; HSPC276 |
NCBI Protein Information: | HBS1-like protein |
UniProt Protein Name: | HBS1-like protein |
UniProt Synonym Protein Names: | ERFS |
Protein Family: | HBS1-like protein |
UniProt Gene Name: | HBS1L |
UniProt Entry Name: | HBS1L_HUMAN |
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