Anti-GULP1 Antibody (CAB3432)
- SKU:
- CAB3432
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
抗体名: | Anti-GULP1 Antibody |
抗体コード: | CAB3432 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human GULP1 (NP_057399.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HT-29, 293T, Mouse lung, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human GULP1 (NP_057399.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MNRA FSRK KDKT WMHT PEAL SKHF IPYN AKFL GSTE VEQP KGTE VVRD AVRK LKFA RHIK KSEG QKIP KVEL QISI YGVK ILEP KTKE VQHN CQLH RISF CADD KTDK RIFT FICK DSES NKHL CYVF DS |
遺伝子ID: | 51454 |
Uniprot: | Q9UBP9 |
セルラーロケーション: | Cytoplasm |
計算された分子量: | 19kDa/22kDa/33kDa/34kDa |
観察された分子量: | 34kDa |
同義語: | GULP1, CED-6, CED6, GULP |
バックグラウンド: | The protein encoded by this gene is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Several transcript variants, some protein coding and some thought not to be protein coding, have been found for this gene. |
UniProt Protein Function: | GULP1: May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6. Belongs to the ced-6 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 2q32.3-q33 Cellular Component: cytoplasm Molecular Function:signal transducer activity Biological Process: apoptosis; phagocytosis, engulfment; lipid transport; signal transduction |
NCBI Summary: | The protein encoded by this gene is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Several transcript variants, some protein coding and some thought not to be protein coding, have been found for this gene. [provided by RefSeq, Nov 2011] |
UniProt Code: | Q9UBP9 |
NCBI GenInfo Identifier: | 74720076 |
NCBI Gene ID: | 51454 |
NCBI Accession: | Q9UBP9.1 |
UniProt Secondary Accession: | Q9UBP9,Q53PC1, Q53RF3, Q9BVL3, B2RB51, B4DQ40, B8ZZ72 D3DPH1, E9PB86, |
UniProt Related Accession: | Q9UBP9 |
Molecular Weight: | 304 |
NCBI Full Name: | PTB domain-containing engulfment adapter protein 1 |
NCBI Synonym Full Names: | GULP, engulfment adaptor PTB domain containing 1 |
NCBI Official Symbol: | GULP1 |
NCBI Official Synonym Symbols: | CED6; GULP; CED-6 |
NCBI Protein Information: | PTB domain-containing engulfment adapter protein 1; cell death protein 6 homolog; PTB domain adapter protein CED-6; PTB domain adaptor protein CED-6 |
UniProt Protein Name: | PTB domain-containing engulfment adapter protein 1 |
UniProt Synonym Protein Names: | Cell death protein 6 homolog; PTB domain adapter protein CED-6; Protein GULP |
Protein Family: | PTB domain-containing engulfment adapter protein |
UniProt Gene Name: | GULP1 |
UniProt Entry Name: | GULP1_HUMAN |
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