Anti-GRIK4 Antibody (CAB13800)
- SKU:
- CAB13800
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-GRIK4 Antibody |
抗体コード: | CAB13800 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-220 of human GRIK4 (NP_055434.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | SH-SY5Y, Mouse brain, Mouse kidney, Rat brain, Rat kidney |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-220 of human GRIK4 (NP_055434.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | SPHS LRIA AILD DPME CSRG ERLS ITLA KNRI NRAP ERLG KAKV EVDI FELL RDSE YETA ETMC QILP KGVV AVLG PSSS PASS SIIS NICG EKEV PHFK VAPE EFVK FQFQ RFTT LNLH PSNT DISV AVAG ILNF FNCT TACL ICAK AECL LNLE KLLR QFLI SKDT LSVR MLDD TRDP TPLL KEIR DDKT ATII IHAN |
遺伝子ID: | 2900 |
Uniprot: | Q16099 |
セルラーロケーション: | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse |
計算された分子量: | 107kDa |
観察された分子量: | 100kDa |
同義語: | GRIK4, EAA1, GRIK, GluK4, KA1, kainate 4 |
バックグラウンド: | This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | GluR KA1: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK4 subfamily. |
UniProt Protein Details: | Protein type:Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 11q22.3 Cellular Component: presynaptic membrane; postsynaptic membrane; kainate selective glutamate receptor complex; integral to plasma membrane; dendrite; plasma membrane; terminal button; perikaryon; cell junction; nucleus Molecular Function:extracellular-glutamate-gated ion channel activity; kainate selective glutamate receptor activity Biological Process: synaptic transmission; synaptic transmission, glutamatergic; glutamate signaling pathway; transport; ionotropic glutamate receptor signaling pathway; response to corticosteroid stimulus |
NCBI Summary: | This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] |
UniProt Code: | Q16099 |
NCBI GenInfo Identifier: | 209572625 |
NCBI Gene ID: | 2900 |
NCBI Accession: | Q16099.2 |
UniProt Secondary Accession: | Q16099,Q8BMF5, Q01812, |
UniProt Related Accession: | Q16099 |
Molecular Weight: | 107,246 Da |
NCBI Full Name: | Glutamate receptor ionotropic, kainate 4 |
NCBI Synonym Full Names: | glutamate receptor, ionotropic, kainate 4 |
NCBI Official Symbol: | GRIK4 |
NCBI Official Synonym Symbols: | KA1; EAA1; GRIK; GluK4 |
NCBI Protein Information: | glutamate receptor ionotropic, kainate 4; glutamate receptor KA1; glutamate receptor KA-1; excitatory amino acid receptor 1 |
UniProt Protein Name: | Glutamate receptor ionotropic, kainate 4 |
UniProt Synonym Protein Names: | Excitatory amino acid receptor 1; EAA1; Glutamate receptor KA-1; KA1 |
UniProt Gene Name: | GRIK4 |
UniProt Entry Name: | GRIK4_HUMAN |
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