Anti-GALK1 Antibody (CAB15274)
- SKU:
- CAB15274
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-GALK1 Antibody |
抗体コード: | CAB15274 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human GALK1 (NP_000145.1). |
申し込み: | WB |
推奨希釈: | WB 1:200 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | U-251MG, HepG2, HeLa, MCF7, Mouse heart, Mouse brain, Mouse lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human GALK1 (NP_000145.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MAAL RQPQ VAEL LAEA RRAF REEF GAEP ELAV SAPG RVNL IGEH TDYN QGLV LPMA LELM TVLV GSPR KDGL VSLL TTSE GADE PQRL QFPL PTAQ RSLE PGTP RWAN YVKG VIQY YPAA |
遺伝子ID: | 2584 |
Uniprot: | P51570 |
セルラーロケーション: | |
計算された分子量: | 42kDa/45kDa |
観察された分子量: | 42kDa |
同義語: | GALK1, GALK, GK1, HEL-S-19 |
バックグラウンド: | Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population. |
UniProt Protein Function: | GALK1: Major enzyme for galactose metabolism. Defects in GALK1 are the cause of galactosemia II (GALCT2). Galactosemia II is an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of galactitol in the lenses. Belongs to the GHMP kinase family. GalK subfamily. |
UniProt Protein Details: | Protein type:Kinase, other; Carbohydrate Metabolism - galactose; EC 2.7.1.6; Carbohydrate Metabolism - amino sugar and nucleotide sugar Chromosomal Location of Human Ortholog: 17q24 Cellular Component: cytoplasm; cytosol; membrane Molecular Function:ATP binding; galactokinase activity; galactose binding Biological Process: galactose catabolic process; galactose metabolic process Disease: Galactokinase Deficiency |
NCBI Summary: | Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population. [provided by RefSeq, Jul 2008] |
UniProt Code: | P51570 |
NCBI GenInfo Identifier: | 1730187 |
NCBI Gene ID: | 2584 |
NCBI Accession: | P51570.1 |
UniProt Secondary Accession: | P51570,B2RC07, B4E1G6, |
UniProt Related Accession: | P51570 |
Molecular Weight: | 45,358 Da |
NCBI Full Name: | Galactokinase |
NCBI Synonym Full Names: | galactokinase 1 |
NCBI Official Symbol: | GALK1 |
NCBI Official Synonym Symbols: | GK1; GALK; HEL-S-19 |
NCBI Protein Information: | galactokinase |
UniProt Protein Name: | Galactokinase |
UniProt Synonym Protein Names: | Galactose kinase |
UniProt Gene Name: | GALK1 |
UniProt Entry Name: | GALK1_HUMAN |
View AllClose