Anti-GABRA5 抗体 (CAB9932)

抗体名:	Anti-GABRA5 Antibody
抗体コード:	CAB9932
抗体サイズ:	20uL, 50uL, 100uL
申し込み:	WB
反応性:	Mouse, Rat
宿主種:	Rabbit
免疫原:	Recombinant fusion protein containing a sequence corresponding to amino acids 32-259 of human GABRA5 (NP_000801.1).

申し込み:	WB
推奨希釈:	WB 1:1000 - 1:4000
反応性:	Mouse, Rat
ポジティブサンプル:	Mouse brain, Mouse skeletal muscle, Mouse pancreas, Rat brain, Rat skeletal muscle

免疫原:	Recombinant fusion protein containing a sequence corresponding to amino acids 32-259 of human GABRA5 (NP_000801.1).
精製方法:	Affinity purification
ストレージバッファ:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:	IgG
順序:	QMPT SSVK DETN DNIT IFTR ILDG LLDG YDNR LRPG LGER ITQV RTDI YVTS FGPV SDTE MEYT IDVF FRQS WKDE RLRF KGPM QRLP LNNL LASK IWTP DTFF HNGK KSIA HNMT TPNK LLRL EDDG TLLY TMRL TISA ECPM QLED FPMD AHAC PLKF GSYA YPNS EVVY VWTN GSTK SVVV AEDG SRLN QYHL MGQT VGTE NIST STGE YTIM TAHF HLKR KIGY
遺伝子ID:	2558
Uniprot:	P31644
セルラーロケーション:	Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
計算された分子量:	52kDa
観察された分子量:	52kDa

同義語:

GABRA5

バックグラウンド:

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.

UniProt Protein Function:	GABRA5: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA5 sub-subfamily.
UniProt Protein Details:	Protein type:Transporter; Membrane protein, multi-pass; Transporter, ion channel; Membrane protein, integral Chromosomal Location of Human Ortholog: 15q12 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:GABA-A receptor activity; receptor activity; transporter activity Biological Process: positive regulation of defense response to virus by host; signal transduction; transport
NCBI Summary:	GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]
UniProt Code:	P31644
NCBI GenInfo Identifier:	15030265
NCBI Gene ID:	2558
NCBI Accession:	BC011403
UniProt Secondary Accession:	P31644,Q14DC2, Q53XL6, Q9NYT3, Q9NYT4, Q9NYT5, A8K338
UniProt Related Accession:	P31644,AAB22608
Molecular Weight:	52,146 Da
NCBI Full Name:	Homo sapiens cDNA clone IMAGE:3868411, ** WARNING: chimeric clone **
NCBI Synonym Full Names:	gamma-aminobutyric acid type A receptor alpha5 subunit
NCBI Official Symbol:	GABRA5
NCBI Protein Information:	gamma-aminobutyric acid receptor subunit alpha-5
UniProt Protein Name:	Gamma-aminobutyric acid receptor subunit alpha-5
UniProt Synonym Protein Names:	GABA(A) receptor subunit alpha-5
Protein Family:	Gamma-aminobutyric acid receptor
UniProt Gene Name:	GABRA5
UniProt Entry Name:	GBRA5_HUMAN

Anti-GABRA5 Polyclonal Antibody (CAB9932)

Western blot analysis of extracts of various cell lines, using GABRA5 antibody (CAB9932) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3s.

Antibodies

Anti-GABRA5 Antibody (CAB13984)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)